完整後設資料紀錄
DC 欄位語言
dc.contributor.authorHorade, Mitsuhiroen_US
dc.contributor.authorTsai, Chia-Hung Dylanen_US
dc.contributor.authorKaneko, Makotoen_US
dc.date.accessioned2019-04-02T05:58:45Z-
dc.date.available2019-04-02T05:58:45Z-
dc.date.issued2019-02-01en_US
dc.identifier.issn2072-666Xen_US
dc.identifier.urihttp://dx.doi.org/10.3390/mi10020133en_US
dc.identifier.urihttp://hdl.handle.net/11536/148997-
dc.description.abstractThis paper proposes a microfluidic device which can perform simultaneous observation on cell growth with and without applying periodic hydrostatic pressure (Yokoyama et al. Sci. Rep. 2017, 7, 427). The device is called on-chip cell incubator. It is known that culture with periodic hydrostatic pressure benefits the elasticity of a cultured cell sheet based on the results in previous studies, but how the cells respond to such a stimulus during the culture is not yet clear. In this work, we focused on cell behavior under periodic hydrostatic pressure from the moment of cell seeding. The key advantage of the proposed device is that we can compare the results with and without periodic hydrostatic pressure while all other conditions were kept the same. According to the results, we found that cell sizes under periodic hydrostatic pressure increase faster than those under atmospheric pressure, and furthermore, a frequency-dependent fluctuation of cell size was found using Fourier analysis.en_US
dc.language.isoen_USen_US
dc.subjecton-chip cell incubatoren_US
dc.subjectperiodic hydrostatic pressureen_US
dc.subjectperiodic pressureen_US
dc.subjecttime-lapse observationen_US
dc.subjectcell growthen_US
dc.subjectsimultaneous multiple chamber observationen_US
dc.titleOn-Chip Cell Incubator for Simultaneous Observation of Culture with and without Periodic Hydrostatic Pressureen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/mi10020133en_US
dc.identifier.journalMICROMACHINESen_US
dc.citation.volume10en_US
dc.contributor.department機械工程學系zh_TW
dc.contributor.departmentDepartment of Mechanical Engineeringen_US
dc.identifier.wosnumberWOS:000460798200058en_US
dc.citation.woscount0en_US
顯示於類別:期刊論文