| 標題: | Identification of inhibitors for the DEDDh family of exonucleases and a unique inhibition mechanism revealed by crystal structure analysis of CRN-4 bound with MES |
| 作者: | Hsiao, Yu-Yuan Huang, Kuan-Wei Hsu, Kai-Cheng Chu, Lee-Ya Yang, Jinn-Moon Yuan, Hanna S. 生物資訊及系統生物研究所 分子醫學與生物工程研究所 Institude of Bioinformatics and Systems Biology Institute of Molecular Medicine and Bioengineering |
| 關鍵字: | Nuclease;Inhibitors;Protein-inhibitor complex;crystal structure;nuclease inhibitor;antiviral drug |
| 公開日期: | 1-一月-2016 |
| URI: | http://dx.doi.org/10.1107/S2053273316096911 http://hdl.handle.net/11536/152599 |
| ISSN: | 2053-2733 |
| DOI: | 10.1107/S2053273316096911 |
| 期刊: | ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES |
| Volume: | 72 |
| 起始頁: | 0 |
| 結束頁: | 0 |
| 顯示於類別： | 期刊論文 |
- Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES) / Huang, Kuan-Wei;Hsu, Kai-Cheng;Chu, Lee-Ya;Yang, Jinn-Moon;Yuan, Hanna S.
- 從NP exonuclease抑制劑複合物結構探討半胱氨酸之共價結合酵素活性抑制機制 / 華梓佑;蕭育源;Hua, Tzu-Yu;Hsiao, Yu-Yuan
- KIDFamMap: a database of kinase-inhibitor-disease family maps for kinase inhibitor selectivity and binding mechanisms / Chiu, Yi-Yuan;Lin, Chih-Ta;Huang, Jhang-Wei;Hsu, Kai-Cheng;Tseng, Jen-Hu
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