Title: | Identification of inhibitors for the DEDDh family of exonucleases and a unique inhibition mechanism revealed by crystal structure analysis of CRN-4 bound with MES |
Authors: | Hsiao, Yu-Yuan Huang, Kuan-Wei Hsu, Kai-Cheng Chu, Lee-Ya Yang, Jinn-Moon Yuan, Hanna S. 生物資訊及系統生物研究所 分子醫學與生物工程研究所 Institude of Bioinformatics and Systems Biology Institute of Molecular Medicine and Bioengineering |
Keywords: | Nuclease;Inhibitors;Protein-inhibitor complex;crystal structure;nuclease inhibitor;antiviral drug |
Issue Date: | 1-Jan-2016 |
URI: | http://dx.doi.org/10.1107/S2053273316096911 http://hdl.handle.net/11536/152599 |
ISSN: | 2053-2733 |
DOI: | 10.1107/S2053273316096911 |
Journal: | ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES |
Volume: | 72 |
Begin Page: | 0 |
End Page: | 0 |
Appears in Collections: | Articles |