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dc.contributor.authorAmbre, Ramen_US
dc.contributor.authorYang, Hsuanen_US
dc.contributor.authorChen, Wen-Chingen_US
dc.contributor.authorYap, Glenn P. A.en_US
dc.contributor.authorJurca, Titelen_US
dc.contributor.authorOng, Tiow-Ganen_US
dc.date.accessioned2019-09-02T07:46:20Z-
dc.date.available2019-09-02T07:46:20Z-
dc.date.issued1970-01-01en_US
dc.identifier.issn1434-1948en_US
dc.identifier.urihttp://dx.doi.org/10.1002/ejic.201900692en_US
dc.identifier.urihttp://hdl.handle.net/11536/152708-
dc.description.abstractThe development of a cross-coupling reaction protocol between aryl ethers and Grignard reagents catalyzed by carbodicarbene (CDC) nickel complexes to afford biaryl compounds through C-O cleavage is reported. Aromatic substrates featuring a broad range of electron neutral, donating, or withdrawing groups are introduced at the desired position. The method has proven effective over a wide range of naphthyl methyl ethers, anisoles, and Grignard reagents. The robustness of the protocol is validated by performing multiple cleavage reactions, gram scale synthesis, and arylation of a dimethoxy esterdiol derivative.en_US
dc.language.isoen_USen_US
dc.subjectCarbene ligandsen_US
dc.subjectC-O Cleavageen_US
dc.subjectCross-couplingen_US
dc.subjectNickelen_US
dc.subjectSynthetic methodsen_US
dc.titleNickel Carbodicarbene Catalyzes Kumada Cross-Coupling of Aryl Ethers with Grignard Reagents through C-O Bond Activationen_US
dc.typeArticleen_US
dc.identifier.doi10.1002/ejic.201900692en_US
dc.identifier.journalEUROPEAN JOURNAL OF INORGANIC CHEMISTRYen_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000478443800001en_US
dc.citation.woscount0en_US
Appears in Collections:Articles