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dc.contributor.authorChen, Pai-Hsien_US
dc.contributor.authorChang, Kuo-Mingen_US
dc.contributor.authorTseng, Wei-Chien_US
dc.contributor.authorChen, Chien-Hungen_US
dc.contributor.authorChao, Jui-Ien_US
dc.date.accessioned2019-12-13T01:09:57Z-
dc.date.available2019-12-13T01:09:57Z-
dc.date.issued1970-01-01en_US
dc.identifier.issn1759-7706en_US
dc.identifier.urihttp://dx.doi.org/10.1111/1759-7714.13199en_US
dc.identifier.urihttp://hdl.handle.net/11536/153043-
dc.description.abstractBackground The early stages of lung cancer with ground-glass opacity (GGO) pattern are detectable. However, it remains a challenge for physicians how best to treat GGO nodules as invasive tumors are occasionally found, even in pure GGO nodules. This study identified the invasiveness by the clinical features of the GGO nodules. Methods A retrospective review of patients with resected GGO nodules from August 2015 to February 2019 was performed. A total of 92 patients were enrolled and gender, age, tumor location, operation times, tumor size, histopathologic and radiological findings were analyzed. Results In this study, the sequential of GGO nodules invasiveness was significantly related to the tumor size and solid component. After regrouping the population into preinvasive and invasive groups, the invasiveness was significantly related to tumor size, solid component, tumor volume and maximal computed tomography (CT) value. Conclusions The invasiveness is difficult to evaluate according to the CT features only when the GGO nodules are less than 2 cm and consolidation/tumor ratio (C/T ratio) are less than 0.25. Tumor size and solid component are significant factors for predicting invasiveness. Part-solid GGO nodules with a diameter greater than 1 cm require surgical consideration due to their high risk of invasiveness.en_US
dc.language.isoen_USen_US
dc.subjectGround-glass opacityen_US
dc.subjectinvasivenessen_US
dc.subjectlung adenocarcinomaen_US
dc.subjectsurgical interventionen_US
dc.titleInvasiveness and surgical timing evaluation by clinical features of ground-glass opacity nodules in lung cancersen_US
dc.typeArticleen_US
dc.identifier.doi10.1111/1759-7714.13199en_US
dc.identifier.journalTHORACIC CANCERen_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department交大名義發表zh_TW
dc.contributor.department生物科技學系zh_TW
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.departmentNational Chiao Tung Universityen_US
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.identifier.wosnumberWOS:000491094300001en_US
dc.citation.woscount0en_US
Appears in Collections:Articles