標題: Surface active flexible palladium nano-thin-film electrode development for biosensing
作者: Chang, Chia-Yu
Huang, Yun-Tzu
Chang, Pang-Chia
Su, Chien-Hao
Hsu, Kuo-Chen
Li, Xing
Wu, Cheng-Han
Chang, Chia-Ching
交大名義發表
生物科技學系
電子物理學系
National Chiao Tung University
Department of Biological Science and Technology
Department of Electrophysics
關鍵字: Pd roughness surface;Pd nano-thin-film electrode;Bio-conjugation enhancement;Nano crystalline electrode;Electrochemical impedance spectroscopy (EIS)
公開日期: 1-Sep-2019
摘要: Metal atoms on surface edges or with specific coordinates possess high surface potentials, and serve as core atoms for organic molecule bonding. However, these active metal atoms may lose their activity by self-diffusion on the surface. A polyethylene terephthalate (PET) substrate provided a stable rough surface in nanoscale for metal atoms absorption and formation of a stable and active nano-thin-film (NTF) surface. However, the NTF surface roughness decreased with increasing thickness of palladium (Pd) granules, indicating that the surface growth of the Pd film followed a Stranski-Krastanov-like growth model. Therefore, the proper thickness of Pd-NTF on PET substrate (Pd NTF-PET) was developed for electrochemical impedance spectroscopy (EIS). Protein was immobilized on the Pd NTF-PET electrodes within 15 min and its biosensing sensitivity was as low as 0.1 ng per-test in 1 mu l. We expect that the developed Pd NTF-PET electrode can be used for other biosensing applications as well.
URI: http://dx.doi.org/10.1016/j.inoche.2019.107461
http://hdl.handle.net/11536/153059
ISSN: 1387-7003
DOI: 10.1016/j.inoche.2019.107461
期刊: INORGANIC CHEMISTRY COMMUNICATIONS
Volume: 107
起始頁: 0
結束頁: 0
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