標題: Impact of patient-related factors on successful autologous fat injection laryngoplasty in thyroid surgical treated related unilateral vocal fold paralysis- observational study
作者: Lin, Wen-Yang
Chang, Wen-Dien
Ko, Li-Wei
Tsou, Yung-An
Chen, Sheng-Hwa
交大名義發表
生物科技學系
National Chiao Tung University
Department of Biological Science and Technology
關鍵字: autologous injection laryngoplasty;unilateral vocal fold paralysis;voice performance
公開日期: 1-一月-2020
摘要: The aim of this study was to compare major voice indicators in different sub-categories, the outcome of lipoinjection for patients might be refined and some voice prognostic factors could be more particularized in specific sub-groups. This is an observational study, and sub-grouped UVFP patients into 3 categories: male vs female, BMI >= 24 vs BMI < 24, Age >= 60 vs Age < 60 for more detailed exploring whether sub-categories affected voice diagnostic and prognostic parameters. Patients' voice data is recorded before and after the autologous fat injection laryngoplasty by a multidimensional voice program. Overall, 73 patients' voice performance were improved 12 months later by vocal fold lipoinjection. In the comparison of the male with female revealed female obtained better Jita than male by surgery (Female: 174.50 +/- 100.58 Hz; Male: 294.82 +/- 253.65 Hz; P < .05). BMI >= 24 vs BMI < 24 showed no statistical difference. Patients aged under 60 demonstrated better Highest F0, lowest F0, NHR and ShdB than elder ones 12 months after receiving vocal fold lipoinjection. Thus, Noise-to-harmonics ratio (NHR), voice turbulence index (VTI), and ShdB (Absolute shimmer, dB) may be the major post-operative evaluating markers of patients' age under 60. Voice parameters showed no significant correlation with BMI. Female patients performed lower Jita (Absolute jitter, mu sec) than male patients 1 year after receiving treatment. The experimental results in this study showed UVFP patients' gender and age may stand as significant categories on analyzing clinical voice prognostic indicators, ShdB and Jita of autologous injection laryngoplasty.
URI: http://dx.doi.org/10.1097/MD.0000000000018579
http://hdl.handle.net/11536/154143
ISSN: 0025-7974
DOI: 10.1097/MD.0000000000018579
期刊: MEDICINE
Volume: 99
Issue: 1
起始頁: 0
結束頁: 0
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