Palladium-catalyzed alpha-arylation of indolin-3-ones

doi:10.1039/d0cc00435a

完整後設資料紀錄

DC 欄位	值	語言
dc.contributor.author	Chang, Yu-Hsuan	en_US
dc.contributor.author	Peng, Wan-Ling	en_US
dc.contributor.author	Chen, I-Chia	en_US
dc.contributor.author	Hsu, Hsin-Yun	en_US
dc.contributor.author	Wu, Yen-Ku	en_US
dc.date.accessioned	2020-07-01T05:21:15Z	-
dc.date.available	2020-07-01T05:21:15Z	-
dc.date.issued	2020-04-30	en_US
dc.identifier.issn	1359-7345	en_US
dc.identifier.uri	http://dx.doi.org/10.1039/d0cc00435a	en_US
dc.identifier.uri	http://hdl.handle.net/11536/154321	-
dc.description.abstract	A method for the catalytic alpha-arylation of indolin-3-ones was developed. The catalytic system comprising Pd(dba)(2) and PAd(3) was found to be optimal for the transformation. The protocol features broad functional group compatibility in that a range of arylated indoxyl derivatives bearing a fully substituted carbon center was synthesized with high efficiency. A preliminary bioassay study revealed that the selected indole-substituted indolin-3-ones exhibit favorable cytotoxic activities against HCT-116 cancer cell line.	en_US
dc.language.iso	en_US	en_US
dc.title	Palladium-catalyzed alpha-arylation of indolin-3-ones	en_US
dc.type	Article	en_US
dc.identifier.doi	10.1039/d0cc00435a	en_US
dc.identifier.journal	CHEMICAL COMMUNICATIONS	en_US
dc.citation.volume	56	en_US
dc.citation.issue	34	en_US
dc.citation.spage	4660	en_US
dc.citation.epage	4663	en_US
dc.contributor.department	應用化學系	zh_TW
dc.contributor.department	Department of Applied Chemistry	en_US
dc.identifier.wosnumber	WOS:000530725500003	en_US
dc.citation.woscount	0	en_US
顯示於類別：	期刊論文