完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wu, Chung-Yi | en_US |
dc.contributor.author | Lin, Hui-Chang | en_US |
dc.contributor.author | Wu, Hsien-Jen | en_US |
dc.date.accessioned | 2014-12-08T15:21:51Z | - |
dc.date.available | 2014-12-08T15:21:51Z | - |
dc.date.issued | 2012-03-04 | en_US |
dc.identifier.issn | 0040-4020 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1016/j.tet.2012.01.055 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/15558 | - |
dc.description.abstract | We synthesized acetal aza-cage compounds directly via ozonolysis of 2,3-bis-endo-diol- and diacylnorbornenes in dichloromethane at -78 degrees C. Ozonolysis of the diols followed by addition of amines gave the aza-cage compounds in high yields. The reaction mechanism for the formation of this type of aza-cage compounds is proposed to proceed via the hydroperoxide intermediate. Ozonolysis of the diacetyl norbornene followed by addition of (1) primary amines gave monoaza-cages and diaza-cage, (2) tert-butylamine gave hydroxyl lactone and diaza-cages, and (3) amino acid ester gave optically active aza-cages, in which one compound was converted into chiral aminoalcohol and structure of another was proven by X-ray analysis. A mechanism via the final ozonide and the imine intermediates is proposed for the formation of this type of aza-cages. (C) 2012 Elsevier Ltd. All rights reserved. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Aza-cage | en_US |
dc.subject | Chiral | en_US |
dc.subject | Ozonolysis | en_US |
dc.subject | Imine | en_US |
dc.subject | X-ray | en_US |
dc.title | Synthesis of new acetal aza-cage compounds via ozonolysis of bis-endo-diol- and diacylnorbornene derivatives | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.tet.2012.01.055 | en_US |
dc.identifier.journal | TETRAHEDRON | en_US |
dc.citation.volume | 68 | en_US |
dc.citation.issue | 9 | en_US |
dc.citation.spage | 2100 | en_US |
dc.citation.epage | 2106 | en_US |
dc.contributor.department | 應用化學系 | zh_TW |
dc.contributor.department | Department of Applied Chemistry | en_US |
dc.identifier.wosnumber | WOS:000301309000003 | - |
dc.citation.woscount | 1 | - |
顯示於類別: | 期刊論文 |