標題: | Protein Secondary Structure Imaging with Ultrabroadband Multiplex Coherent Anti-Stokes Raman Scattering (CARS) Microspectroscopy |
作者: | Bito, Kotatsu Okuno, Masanari Kano, Hideaki Tokuhara, Shihomi Naito, Satoru Masukawa, Yoshinori Leproux, Philippe Couderc, Vincent Hamaguchi, Hiro-o 應用化學系 應用化學系分子科學碩博班 Department of Applied Chemistry Institute of Molecular science |
公開日期: | 2-二月-2012 |
摘要: | Protein secondary structures in human hair have been studied with ultrabroadband multiplex coherent anti-Stokes Raman scattering (CARS) microspectroscopy. The CARS peak-shift mapping method has been developed and applied to hair samples with and without treatments by chemical reduction and mechanical extension. It clearly visualizes the treatment induced changes in protein secondary structures and their spatial distributions. Using the new imaging technique, we found a multilayered structure in the human hair cortex. |
URI: | http://dx.doi.org/10.1021/jp210914x http://hdl.handle.net/11536/15641 |
ISSN: | 1520-6106 |
DOI: | 10.1021/jp210914x |
期刊: | JOURNAL OF PHYSICAL CHEMISTRY B |
Volume: | 116 |
Issue: | 4 |
起始頁: | 1452 |
結束頁: | 1457 |
顯示於類別: | 期刊論文 |