Acyl and Silyl Group Effects in Reactivity-Based One-Pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc(4) and IV(2)Fuc-Lc(4)

標題:	Acyl and Silyl Group Effects in Reactivity-Based One-Pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc(4) and IV(2)Fuc-Lc(4)
作者:	Hsu, Yun Lu, Xin-An Zulueta, Medel Manuel L. Tsai, Chih-Ming Lin, Kuo-I Hung, Shang-Cheng Wong, Chi-Huey 應用化學系 Department of Applied Chemistry
公開日期:	14-三月-2012
摘要:	Relative reactivity evaluations showed the graded arming of toluenyl thioglucosides by variously positioned silyl groups but not by their acyl counterparts. These findings were applied in reactivity-based one-pot assembly of linker-attached Lc(4) and IV(2)Fuc-Lc(4), which are components of human embryonic stem cell surface. The sugar-galectin-1 binding was also examined.
URI:	http://dx.doi.org/10.1021/ja300284x http://hdl.handle.net/11536/15802
ISSN:	0002-7863
DOI:	10.1021/ja300284x
期刊:	JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume:	134
Issue:	10
起始頁:	4549
結束頁:	4552
顯示於類別：	期刊論文

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