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dc.contributor.authorChan, Po-Hanen_US
dc.contributor.authorChen, Yu-Chieen_US
dc.date.accessioned2014-12-08T15:28:31Z-
dc.date.available2014-12-08T15:28:31Z-
dc.date.issued2012-11-06en_US
dc.identifier.issn0003-2700en_US
dc.identifier.urihttp://dx.doi.org/10.1021/ac302417ken_US
dc.identifier.urihttp://hdl.handle.net/11536/20624-
dc.description.abstractIn this work, human serum albumin (HSA) stabilized gold nanoclusters (HSA-AuNCs) with reddish photoluminescence were used as sensing probes for pathogenic bacteria including Enterobacter cloacae, Escherichia coli J96, Pseudomonas aeruginosa, pandrug-resistant Acinetobacter baumannii (PDRAB), Staphylococcus aureus, methicillin-resistant S. aureus (MASA), Streptococcus pyogenes, and vancomycin-resistant Enterococcus faecalis (VRE). We discovered that HSA-AuNCs have unique affinity with S. aureus and MASA In addition to demonstrating the selective sensing ability of HSA-AuNCs toward S. aureus and MRSA, the binding peptide motifs identified from HSA-AuNCs were characterized by mass spectrometry. The identified binding peptides were further used as the reducing and stabilizing agents for generation of peptide-bound AuNCs (Pep-AuNCs). The generated Pep-AuNCs were demonstrated to have the binding affinities with S. aureus and MRSA.en_US
dc.language.isoen_USen_US
dc.titleHuman Serum Albumin Stabilized Gold Nanoclusters as Selective Luminescent Probes for Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureusen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/ac302417ken_US
dc.identifier.journalANALYTICAL CHEMISTRYen_US
dc.citation.volume84en_US
dc.citation.issue21en_US
dc.citation.spage8952en_US
dc.citation.epage8956en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000310664600010-
dc.citation.woscount14-
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