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dc.contributor.authorWang, Jieen_US
dc.contributor.authorZhuang, Jialien_US
dc.contributor.authorIyer, Sowmyaen_US
dc.contributor.authorLin, Xin-Yingen_US
dc.contributor.authorGreven, Melissa C.en_US
dc.contributor.authorKim, Bong-Hyunen_US
dc.contributor.authorMoore, Jillen_US
dc.contributor.authorPierce, Brian G.en_US
dc.contributor.authorDong, Xianjunen_US
dc.contributor.authorVirgil, Danielen_US
dc.contributor.authorBirney, Ewanen_US
dc.contributor.authorHung, Jui-Hungen_US
dc.contributor.authorWeng, Zhipingen_US
dc.date.accessioned2014-12-08T15:28:44Z-
dc.date.available2014-12-08T15:28:44Z-
dc.date.issued2013-01-01en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttp://dx.doi.org/10.1093/nar/gks1221en_US
dc.identifier.urihttp://hdl.handle.net/11536/20798-
dc.description.abstractThe Encyclopedia of DNA Elements (ENCODE) consortium aims to identify all functional elements in the human genome including transcripts, transcriptional regulatory regions, along with their chromatin states and DNA methylation patterns. The ENCODE project generates data utilizing a variety of techniques that can enrich for regulatory regions, such as chromatin immunoprecipitation (ChIP), micrococcal nuclease (MNase) digestion and DNase I digestion, followed by deeply sequencing the resulting DNA. As part of the ENCODE project, we have developed a Web-accessible repository accessible at http://factorbook.org. In Wiki format, factorbook is a transcription factor (TF)-centric repository of all ENCODE ChIP-seq datasets on TF-binding regions, as well as the rich analysis results of these data. In the first release, factorbook contains 457 ChIP-seq datasets on 119 TFs in a number of human cell lines, the average profiles of histone modifications and nucleosome positioning around the TF-binding regions, sequence motifs enriched in the regions and the distance and orientation preferences between motif sites.en_US
dc.language.isoen_USen_US
dc.titleFactorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortiumen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/nar/gks1221en_US
dc.identifier.journalNUCLEIC ACIDS RESEARCHen_US
dc.citation.volume41en_US
dc.citation.issueD1en_US
dc.citation.spageD171en_US
dc.citation.epageD176en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.department生物資訊及系統生物研究所zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.contributor.departmentInstitude of Bioinformatics and Systems Biologyen_US
dc.identifier.wosnumberWOS:000312893300024-
dc.citation.woscount24-
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