標題: | Species distribution and drug susceptibilities of Candida isolates in TSARY 2010 |
作者: | Yang, Yun-Liang Chen, Hui-Ting Lin, Chih-Chao Chu, Wen-Li Lo, Hsiu-Jung 生物科技學系 分子醫學與生物工程研究所 Department of Biological Science and Technology Institute of Molecular Medicine and Bioengineering |
關鍵字: | Antifungal;Candida species;Drug susceptibility |
公開日期: | 1-六月-2013 |
摘要: | Susceptibilities to antifungal drugs of 1083 Candida isolates collected in Taiwan Surveillance of Antimicrobial Resistance of Yeasts in 2010 were determined. There were 422 (39%) C albicans, 270 (24.9%) C tropicalis, 258 (23.8%) C glabrata, 87 (8%) C. parapsilosis, 18 (1.7%) C. krusei, and 28 (2.6%) of 13 other species. In the present study, we have applied species-specific clinical breakpoints for common species and epidemiological cutoff values for rare species. We found that majority of isolates were susceptible to tested drugs. A total of 15, 3, 2, and 0 isolates were not susceptible to fluconazole, voriconazole, amphotericin B, and anidulafungin, respectively. We found that three of the four fluconazole non-susceptible C albicans isolates were resistant to voriconazole. Hence, there is an issue of cross-resistance among azole-type drugs. (C) 2013 Elsevier Inc. All rights reserved. |
URI: | http://dx.doi.org/10.1016/j.diagmicrobio.2013.03.003 http://hdl.handle.net/11536/22332 |
ISSN: | 0732-8893 |
DOI: | 10.1016/j.diagmicrobio.2013.03.003 |
期刊: | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE |
Volume: | 76 |
Issue: | 2 |
起始頁: | 182 |
結束頁: | 186 |
顯示於類別: | 期刊論文 |