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dc.contributor.authorYang, Yun-Liangen_US
dc.contributor.authorLiu, Yi-Wenen_US
dc.contributor.authorChen, Hui-Tingen_US
dc.contributor.authorTsai, Moan-Shaneen_US
dc.contributor.authorChu, Wen-Lien_US
dc.contributor.authorLo, Hsiu-Jungen_US
dc.date.accessioned2014-12-08T15:32:53Z-
dc.date.available2014-12-08T15:32:53Z-
dc.date.issued2013-11-01en_US
dc.identifier.issn1369-3786en_US
dc.identifier.urihttp://dx.doi.org/10.3109/13693786.2013.800240en_US
dc.identifier.urihttp://hdl.handle.net/11536/22940-
dc.description.abstractAmong 32 Trichosporon asahii isolates collected in four rounds of the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) studies, conducted in 1999, 2002, 2006, and 2010, five different intergenic spacer 1 (IGS1) genotypes were detected. Genotype 1 was the most common (43.8%), followed by genotypes 3 (28.1%), 7 (12.5%), 5 (9.4%), and 4 (6.3%). Interestingly, genotype 7 was more prevalent in Taiwan than in other areas (P = 0.01); while we did not find a significant association between IGS1 genotype and susceptibility to antifungal drugs, we did note that the majority of isolates of T. asahii were susceptible to both fluconazole and voriconazole, consistent with previous reports. A higher proportion of isolates (P = 0.05) collected in 2010 (4/12, 33.3%) had high amphotericin B MICs (>= 2 mg/l) than those collected in the previous three TSARYs (1/21, 5%). Hence, the new data of genotypes and drug susceptibilities in the present study may contribute to the epidemiology of T. asahiien_US
dc.language.isoen_USen_US
dc.subjectTrichosporonen_US
dc.subjectintergenic spacer 1en_US
dc.subjectgenotypesen_US
dc.subjectIGS1en_US
dc.subjectTrichosporon asahiien_US
dc.titleGenotype analysis based on intergenic spacer 1 sequences of Trichosporon asahii collected in Taiwanen_US
dc.typeArticleen_US
dc.identifier.doi10.3109/13693786.2013.800240en_US
dc.identifier.journalMEDICAL MYCOLOGYen_US
dc.citation.volume51en_US
dc.citation.issue8en_US
dc.citation.spage880en_US
dc.citation.epage883en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.identifier.wosnumberWOS:000325891200013-
dc.citation.woscount0-
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