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dc.contributor.authorChang, Chin-Fuen_US
dc.contributor.authorLi, Chao-Juien_US
dc.contributor.authorKo, Chih-Janen_US
dc.contributor.authorTeng, Tsung-Hanen_US
dc.contributor.authorLai, Shih-Changen_US
dc.contributor.authorYang, Mei-Chuehen_US
dc.contributor.authorChiu, Chun-Wenen_US
dc.contributor.authorChou, Chu-Chungen_US
dc.contributor.authorChang, Chih-Yuen_US
dc.contributor.authorYao, Yung-Chiaoen_US
dc.contributor.authorWu, Lan-Hsinen_US
dc.contributor.authorWu, Han-Pingen_US
dc.contributor.authorChen, Wen-Liangen_US
dc.contributor.authorLin, Yan-Renen_US
dc.date.accessioned2014-12-08T15:33:01Z-
dc.date.available2014-12-08T15:33:01Z-
dc.date.issued2013-10-04en_US
dc.identifier.issn1932-6203en_US
dc.identifier.urihttp://dx.doi.org/10.1371/journal.pone.0075172en_US
dc.identifier.urihttp://hdl.handle.net/11536/22993-
dc.description.abstractObjective: To analyze whether urine output and urinalysis results are predictive of survival and neurologic outcomes in patients with non-traumatic out-of-hospital cardiac arrest (OHCA). Methods: Information was obtained from 1,340 patients with non-traumatic OHCA who had achieved a sustained return of spontaneous circulation (ROSC). Factors that were associated with survival in the post-resuscitative period were evaluated. The association between urine output and fluid challenge in the early resuscitative period was analyzed and compared between the survivors and the non-survivors. The results of the initial urinalysis, including the presence of proteinuria and other findings, were used to evaluate the severity of vascular protein leakage and survival. The association between proteinuria and the neurologic outcomes of the survivors was also analyzed. The clinical features of capillary leakage were examined during the post-resuscitative period. Results: Of the 1,340 patients, 312 survived. A greater urine output was associated with a higher chance of survival. The initial urine output increased in proportion to the amount of fluid that was administered during early resuscitation in the emergency department for the survivors but not for the non-survivors (p<0.05). In the initial urinalysis, proteinuria was strongly associated with survival, and severe proteinuria indicated significantly poorer neurologic outcomes (p<0.05 for both comparisons). Proteinuria was associated with a risk of developing signs of capillary leakage, including body mass index gain and pitting edema (both p<0.001). Conclusion: The severity of proteinuria during the early post-resuscitative period was predictive of survival.en_US
dc.language.isoen_USen_US
dc.titleThe Post-Resuscitative Urinalysis Associate the Survival of Patients with Non-Traumatic Out-of-Hospital Cardiac Arresten_US
dc.typeArticleen_US
dc.identifier.doi10.1371/journal.pone.0075172en_US
dc.identifier.journalPLOS ONEen_US
dc.citation.volume8en_US
dc.citation.issue10en_US
dc.citation.epageen_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.identifier.wosnumberWOS:000325489100029-
dc.citation.woscount0-
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