標題: | Preparation of a Protected 3-Deoxy-D-manno-oct-2-ulosonate Glycal Donor for the Synthesis of beta-KDO-Containing Oligosaccharides |
作者: | Pradhan, Tapan Kumar Lin, Chun Cheng Mong, Kwok-Kong Tony 應用化學系 Department of Applied Chemistry |
公開日期: | 7-三月-2014 |
摘要: | A practical method for the synthesis of KDO glycal donors was developed. The prepared KDO donors exhibited excellent disastereoselectivity of glycosylation in a CH2Cl2-CH3CN solvent mixture, which was found to be associated with the isopropylidene protection at the C-4 and C-5 hydroxyls. The synthetic use of the KDO donor was demonstrated in the preparation of beta-KDO-containing oligosaccharides. |
URI: | http://dx.doi.org/10.1021/ol500275j http://hdl.handle.net/11536/23988 |
ISSN: | 1523-7060 |
DOI: | 10.1021/ol500275j |
期刊: | ORGANIC LETTERS |
Volume: | 16 |
Issue: | 5 |
起始頁: | 1474 |
結束頁: | 1477 |
顯示於類別: | 期刊論文 |