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dc.contributor.authorBarve, Indrajeet J.en_US
dc.contributor.authorChen, Chih-Hauen_US
dc.contributor.authorKao, Chih-Hsienen_US
dc.contributor.authorSun, Chung-Mingen_US
dc.date.accessioned2014-12-08T15:36:06Z-
dc.date.available2014-12-08T15:36:06Z-
dc.date.issued2014-05-01en_US
dc.identifier.issn2156-8952en_US
dc.identifier.urihttp://dx.doi.org/10.1021/co400159zen_US
dc.identifier.urihttp://hdl.handle.net/11536/24454-
dc.description.abstractA novel tandem imination-isocyanate-mediated annulation was explored. Ionic liquid-immobilized 2-aminobenzimidazoles react sequentially with aldehydes and isocyanates to give highly functionalized benzimidazole-embedded triazines. The second-stage transformation revealed that the formation of triazinone functionality is entirely regioselective to allow rapid assembly of biologically interesting tricyclic skeletons. In conjunction with the application of microwave irradiation and IL support, this method provides an efficient route to access substituted benzoimidazotriazines.en_US
dc.language.isoen_USen_US
dc.subjecttandem reactionen_US
dc.subjectiminationen_US
dc.subjectisocyanate-mediated annulationen_US
dc.subjectbenzoimidazotriazineen_US
dc.subjectionic liquiden_US
dc.subjectmicrowaveen_US
dc.titleRegioselective Piperidine-Catalyzed Tandem Imination-Isocyanate Annulation to Fused Tricyclic Triazinesen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/co400159zen_US
dc.identifier.journalACS COMBINATORIAL SCIENCEen_US
dc.citation.volume16en_US
dc.citation.issue5en_US
dc.citation.spage244en_US
dc.citation.epage249en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000335940000008-
dc.citation.woscount1-
Appears in Collections:Articles


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