標題: | Mechanistic Study of a Switch in the Regioselectivity of Hydroheteroarylation of Styrene Catalyzed by Bimetallic Ni-Al through C-H Activation |
作者: | Chen, Wen-Ching Lai, Ying-Chieh Shih, Wei-Chun Yu, Ming-Shiuan Yap, Glenn P. A. Ong, Tiow-Gan 應用化學系 Department of Applied Chemistry |
關鍵字: | alkenes;C-H bond activation;homogeneous catalysis;nickel;regioselectivity |
公開日期: | 23-六月-2014 |
摘要: | We previously reported a highly efficient protocol for bimetallic Ni-Al-catalyzed hydroheteroarylation of styrene with benzimidazole based on C-H bond activation. We have now delineated the mechanism of this process, providing a rationale for an observed switch in regioselectivity in the presence of the Lewis acid, AlMe3. The present mechanistic study gives insights for the rational development of catalysts that exhibit required linear/branched selectivity. |
URI: | http://dx.doi.org/10.1002/chem.201400303 http://hdl.handle.net/11536/24638 |
ISSN: | 0947-6539 |
DOI: | 10.1002/chem.201400303 |
期刊: | CHEMISTRY-A EUROPEAN JOURNAL |
Volume: | 20 |
Issue: | 26 |
起始頁: | 8099 |
結束頁: | 8105 |
顯示於類別: | 期刊論文 |