A new approach to nicotine: Symmetry consideration for synthesis design

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DC 欄位	值	語言
dc.contributor.author	Ho, TL	en_US
dc.contributor.author	Kuzakov, EV	en_US
dc.date.accessioned	2014-12-08T15:39:54Z	-
dc.date.available	2014-12-08T15:39:54Z	-
dc.date.issued	2004	en_US
dc.identifier.issn	0018-019X	en_US
dc.identifier.uri	http://hdl.handle.net/11536/27261	-
dc.identifier.uri	http://dx.doi.org/10.1002/hlca.200490241	en_US
dc.description.abstract	A synthesis of nicotyrine (9), and hence formally racemic nicotine, was carried out by elaboration of the 1:1 adduct 2 of cycloocta-1,5-diene and chlorosulfonyl isocyanate (ClSO2-NCO). Transformation of adduct 2 into carbamate 4 was followed by ozonolysis, tosylation, and NaH treatment, which led to pyrrolidinylpiperidinone 6. LiAlH4 Reduction, debenzylation, and aromatization yielded 2.	en_US
dc.language.iso	en_US	en_US
dc.title	A new approach to nicotine: Symmetry consideration for synthesis design	en_US
dc.type	Article	en_US
dc.identifier.doi	10.1002/hlca.200490241	en_US
dc.identifier.journal	HELVETICA CHIMICA ACTA	en_US
dc.citation.volume	87	en_US
dc.citation.issue	10	en_US
dc.citation.spage	2712	en_US
dc.citation.epage	2716	en_US
dc.contributor.department	應用化學系	zh_TW
dc.contributor.department	Department of Applied Chemistry	en_US
dc.identifier.wosnumber	WOS:000224935400020	-
dc.citation.woscount	6	-
顯示於類別：	期刊論文

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