腦網路基因表現圖譜視覺化研究創作 -以多媒體影片作為科普的表現媒材

Abstract

本論文為以電腦多媒體影片為媒材，來介紹清華大學的“腦科學研究中心”的研究成果。腦科學是本世紀最重要的尖端科技之一，“腦科學研究中心”的「果蠅腦神經基因體計畫」，計畫以五年的時間完成整個果蠅腦神經網路立體模型圖形，並將建立的技術進一步應用於建構老鼠及人腦圖譜，以助於瞭解人腦神經網路及基因表現分佈與其功能之間的關係。 本研究創作為台灣科普創作的一個嶄新成果，目的在於將艱深難懂的腦科學研究，以有趣的、美感的電腦多媒體影片，呈現給一般民眾欣賞。「果蠅腦神經基因體計畫」中的3D生物顯微影像技術，不僅是全世界的先進科技，也開創了科學藝術影像的新視野｡ 因此本研究創作在製作過程中包含幾個要素：1、透過視覺的感知，2、3D腦神經的VR技術，3、網路基因互動，4、精緻的影像設計。本研究創作希望以清晰的結構，透過生動簡短的影片內容，來達到闡釋科普的義意與功能。 節目分為四個大段落：前言，清華大學腦科學中心，Hunting for Memory Circuit 及願景。本節目的執行過程，從企劃、創意構思，到文案、分鏡腳本製作，內容則包含有基因互動、音樂剪輯、旁白口述、電腦2D動畫、3D動畫、影片拍攝、實物拍攝、電視採訪…等。節目中也會呈現出本研究計劃案的近程成果。第三、四章中更詳細說明了各階段的製作內容與多媒體影片各元素的製作方式。在整個製作過程中，還需不斷的修正節目內容，並評估各項預期的成效，最後對於本研究創作的成果與預期的目標的差距提出檢驗與改善，以做為日後以多媒體影片為科普媒材的建議。

Abstract In this thesis, the researcher utilize the personal-computer-based multimedia facility as a stage to present the research achievement of the Brain Research Center in the National Tsing Hua University. The brain science is one of the most important frontier researches in the world. The Fly Brain Neurogenomics project in the Brain Research Center plans to construct the whole neural network in fruit flies (Drosophila) into a 3D graphic model. The technique developed in this project will further be used to construct cellular maps for the rat brain and even the human brain. With the help of such knowledge, the neural network and the distribution of its gene expression in human brains, together with their relationships with the brain function, will be clarified. The current production study represents a refreshing result out of works for popular science in Taiwan. Our purpose was to present the profoundly difficult research in brain science to the lay people through a multimedia film with an elating and aesthetic flavor. The biological 3D microscopic imaging technology developed in the Fly Brain Neurogenomics is not only in the frontier of scientific research globally but also provides a new vision in the artistic scientific graphs. There were some elements in my production study: (1) visual oriented content, (2) virtual reality technology for the 3D neural system in fly brains, (3) an interactive gene map on the internet and (4) elegant image design. It was hoped that through the lively but concise context in this film, a clear frame may be sketched so that popular science might be interpreted to the general public, as this piece of work expect to serve. There were four sections in the program: introduction, the Brain Research Center in the Tsing Hua University, hunting for memory circuit and prospects. The production procedures included management, creative thinking, manuscript and production script writing. The content had gene interaction, music splicing, voice over, computer 2D/ 3D animation, movie/ photography making and television interviews. The most current achievement of the scientific research was also mentioned in the film. There were more detailed descriptions on the production of the film and multimedia elements at various stages in Chap. 3 and 4 of the thesis. The work constantly required modifications in the content and assessment for the anticipated effects. Finally, there were examination and reflection on some consequences that might have deviated from the expectation in this production study. The suggestions and advices will be use to improve the multimedia production as the expression of popular science in the future.