標題: | Joined use of oxazolidinone and desymmetric amino protection: a new strategy for protection of glucosamine |
作者: | Lin, Shih-Che Chao, Chin-Sheng Chang, Chiu-Ching Mong, Kwok-Kong T. 應用化學系 Department of Applied Chemistry |
公開日期: | 7-四月-2010 |
摘要: | Joined use of N-benzyl oxazolidinone and N-benzyl-N-benzyloxycarbonyl (N-BnCbz) desymmetric amino-protecting function is reported. The new synthetic approach enables the facile preparation of type I and type 2 LacNAc disaccharides in satisfactory yields. One-pot deprotection of N-BnCbz and O-benzyl ether is achieved by hydrogenolysis under mild conditions. (C) 2010 Elsevier Ltd. All rights reserved. |
URI: | http://dx.doi.org/10.1016/j.tetlet.2010.02.021 http://hdl.handle.net/11536/5522 |
ISSN: | 0040-4039 |
DOI: | 10.1016/j.tetlet.2010.02.021 |
期刊: | TETRAHEDRON LETTERS |
Volume: | 51 |
Issue: | 14 |
起始頁: | 1910 |
結束頁: | 1913 |
顯示於類別: | 期刊論文 |