標題: Joined use of oxazolidinone and desymmetric amino protection: a new strategy for protection of glucosamine
作者: Lin, Shih-Che
Chao, Chin-Sheng
Chang, Chiu-Ching
Mong, Kwok-Kong T.
應用化學系
Department of Applied Chemistry
公開日期: 7-四月-2010
摘要: Joined use of N-benzyl oxazolidinone and N-benzyl-N-benzyloxycarbonyl (N-BnCbz) desymmetric amino-protecting function is reported. The new synthetic approach enables the facile preparation of type I and type 2 LacNAc disaccharides in satisfactory yields. One-pot deprotection of N-BnCbz and O-benzyl ether is achieved by hydrogenolysis under mild conditions. (C) 2010 Elsevier Ltd. All rights reserved.
URI: http://dx.doi.org/10.1016/j.tetlet.2010.02.021
http://hdl.handle.net/11536/5522
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.02.021
期刊: TETRAHEDRON LETTERS
Volume: 51
Issue: 14
起始頁: 1910
結束頁: 1913
顯示於類別:期刊論文


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