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dc.contributor.authorMaiti, Barnalien_US
dc.contributor.authorChanda, Kaushiken_US
dc.contributor.authorSun, Chung-Mingen_US
dc.date.accessioned2014-12-08T15:08:17Z-
dc.date.available2014-12-08T15:08:17Z-
dc.date.issued2009-11-05en_US
dc.identifier.issn1523-7060en_US
dc.identifier.urihttp://dx.doi.org/10.1021/ol901857hen_US
dc.identifier.urihttp://hdl.handle.net/11536/6443-
dc.description.abstractA novel ionic liquid (IL) supported, green synthetic protocol has been developed toward the synthesis of oxo and thio hydantoin analogues tethered with tetrahydro-beta-carboline by the use of focused microwave irradiation. IL-bound tryptophan underwent a Pictet-Spengler reaction with various carbonyl compounds to generate the IL-immobilized tetrahydro-beta-carbolines in aqueous isopropanol media. Subsequent reaction of substituted tetra hydro-beta-carboline derivatives with various isocyanates and isothiocyanate provided a three-dimensional combinatorial library in a traceless fashion.en_US
dc.language.isoen_USen_US
dc.titleTraceless Synthesis of Hydantoin Fused Tetrahydro-beta-carboline on Ionic Liquid Support in Green Mediaen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/ol901857hen_US
dc.identifier.journalORGANIC LETTERSen_US
dc.citation.volume11en_US
dc.citation.issue21en_US
dc.citation.spage4826en_US
dc.citation.epage4829en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000271097100016-
dc.citation.woscount32-
Appears in Collections:Articles


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