标题: 以奈/微米磁域为基础所建构之磁珠操控技术
Micro/Nanoscale Magnetic-Domain-Configured Magnetic Bead Manipulation
作者: 劉子瑋
Liu, Tzu-Wei
鍾添淦
Chung, Tien-Kan
機械工程系所
关键字: 磁性奈/微米结构;磁域;磁性轨道;磁珠操控;实验室晶片;生物微机电;magnetic nano/micro structures;magnetic domains;magnetic track/rail;magnetic bead manipulation;lab-on-chip;bio-MEMS
公开日期: 2014
摘要: 本论文致力于观测超顺磁性磁珠于可变磁场下于各式奈/微米尺度下之单一磁域(Magnetic Single Domain)为基础之轨道上的运动。磁珠之运动行为透过高倍率光学显微镜进行观察。经由观察结果,可以得知磁珠能吸附于本研究所制作之磁域轨道上,并且于大部分的情况下,磁珠内部之磁偶极会在改变外加磁场方向后倾向于顺着磁场方向排列;由此,磁珠会吸附于单一磁域上区域性杂散磁场比较大的磁极上。然而,有时候磁珠会吸附于单一磁域区域性杂散磁场比较小的磁极上。针对此,我认为磁珠可能在切换磁场的过程中,因为磁珠于流体中受局限之布朗运动而移动至靠近区域性杂散磁场比较小的磁极的区域,导致于磁场切换后磁珠会吸附于磁域上磁场强度较弱的磁极上。这些研究结果为未来开发用于生物微机电实验室晶片之磁珠操控系统的核心技术。
This thesis aims to observe a superparamagnetic bead motion on the top of varies micro/nanoscale magnetic single-domain tracks under varies magnetic fields. The bead motion is observed by utilizing a high-magnification optical microscope. We find out that the bead can be trapped to the proposed magnetic-domain tracks. In most cases, after varying the applied magnetic field direction, the magnetic dipoles inside the bead will tend to align with the magnetic field direction, and thereby the bead will be trapped on one of the single-domain’s magnetic pole which has a larger local stray field. However, in some cases, the bead will be trapped to the single-domain’s magnetic pole with relatively small local stray field. According to this, we think that during the switching of the applied magnetic field direction, the bead randomly moved to a location near the small stray-field magnetic pole due to the confined Brownian motion of the bead. Therefore, after the applied magnetic field direction is switched, the bead is trapped on the small-stray magnetic pole. These experimental results are important core technologies to develop future magnetic bead manipulation for bio-MEMS lab-on-chip systems.
URI: http://140.113.39.130/cdrfb3/record/nctu/#GT070251101
http://hdl.handle.net/11536/76436
显示于类别:Thesis