以介電濕潤及液體介電泳實現數位及類比整合微流體晶片

Abstract

電動力是一跨尺度的操作力量，本研究將之應用於實驗室晶片，成功地將以兩種不同的液體驅動力製作在同一晶片上。介電濕潤是一種數位流體系統。另外液體介電泳則是一種驅動流體的方式，我們可視它為一種連續流體系統。其主要優點包含不需流道設計與製程簡單等等。

本研究以結合數位流體和連續流體在同一微流體晶片上，分別藉由介電濕潤以及液體介電泳。並且利用兩種技術的結合，達成奈/微液滴產生系統。除此之外也提供了液體介電泳和毛細管電泳之結合規劃，希望能夠實現在虛擬流道完成DNA之分離。

Electrokinetic force is a cross-scale manipulation mechanism. In this research, we applied the electrokinetic force in Lab-on-a-Chip and succeed to combibe two kinds of liquid actuation. Electrowetting-on-dielectric(EWOD) is a digital microfluidic system. On the other hand, Liquid-dielectrophoresis(LDEP) is also a method for driving fluids, and we could see it as an analog microfluidic system. Advantages of these techniques including non-designing-channel and easily-process.

In this research, we combined digital microfluids and analog microfluids on a single chip by using EWOD and LDE. By using these techniques, we succeed to obtain a nano/micro-droplet-creating-system. Otherwise, we also hope to separate DNA in a virtual-channel by combing LDEP and capillary electrophorseis(CE).