標題: | Susceptibilities to amphotericin B and fluconazole of Candida species in Taiwan Surveillance of Antimicrobial Resistance of Yeasts 2006 |
作者: | Yang, Yun-Liang Wang, An-Huei Wang, Chih-Wei Cheng, Wei-Ting Li, Shu-Ying Lo, Hsiu-Jung 生物科技學系 Department of Biological Science and Technology |
關鍵字: | Candida;susceptibility;resistance |
公開日期: | 1-六月-2008 |
摘要: | Susceptibilities to amphotericin B and fluconazole of 964 Candida isolates collected in Taiwan Surveillance of Antimicrobial Resistance of Yeasts in 2006 were determined. There were 419 (43.5%) Candida albicans, 246 (25.5%) Candida tropicalis, 211 (21.9%) Candida glabrata, 62 (6.4%) Candida parapsilosis, 14 (1.5%) Candida krusei, and 12 (1.2%) others. Interestingly, 16 of the 17 amphotericin B-resistant isolates were non-albicans Candida species. The resistant rate to amphotericin B has decreased from 2.5% in 2002 to 1.8% in 2006. On the other hand, there were 132 C. tropicalis, 14 C. krusei, 10 C. albicans, and 9 C. glabrata isolates that had MICs to fluconazole >= 64 mu g/mL. The prevalence of isolates with such high MICs was significantly higher than that in 2002 (17.1% versus 1.9%). Our results further indicate that most of the isolates with MICs to fluconazole >= 64 mu g/mL exhibited the "trailing" phenomenon. (C) 2008 Elsevier Inc. All rights reserved. |
URI: | http://dx.doi.org/10.1016/j.diagmicrobio.2008.01.011 http://hdl.handle.net/11536/8749 |
ISSN: | 0732-8893 |
DOI: | 10.1016/j.diagmicrobio.2008.01.011 |
期刊: | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE |
Volume: | 61 |
Issue: | 2 |
起始頁: | 175 |
結束頁: | 180 |
顯示於類別: | 期刊論文 |