One-Pot, Two-Step Synthesis of Imidazo[1,2-a]benzimidazoles via A Multicomponent [4+1] Cycloaddition Reaction
| dc.citation.epage | 555 | en_US |
| dc.citation.issue | 10 | en_US |
| dc.citation.spage | 551 | en_US |
| dc.citation.volume | 15 | en_US |
| dc.citation.woscount | 3 | |
| dc.contributor.author | Hsiao, Ya-Shan | en_US |
| dc.contributor.author | Narhe, Bharat D. | en_US |
| dc.contributor.author | Chang, Ying-Sheng | en_US |
| dc.contributor.author | Sun, Chung-Ming | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:33:03Z | |
| dc.date.available | 2014-12-08T15:33:03Z | |
| dc.date.issued | 2013-10-01 | en_US |
| dc.description.abstract | A one-pot, two-step synthesis of imidazo[1,2-a]benzimidazoles has been achieved by a three-component reaction of 2-aminobenzimidazoles with an aromatic aldehyde and an isocyanide. The reaction involving condensation of 2-aminobenzimidazole with an aldehyde is run under microwave activation to generate an imine intermediate under basic conditions which then undergoes [4 + 1] cycloaddition with an isocyanide. | en_US |
| dc.identifier.doi | 10.1021/co400075z | en_US |
| dc.identifier.issn | 2156-8952 | en_US |
| dc.identifier.journal | ACS COMBINATORIAL SCIENCE | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1021/co400075z | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/23007 | |
| dc.identifier.wosnumber | WOS:000325785400006 | |
| dc.language.iso | en_US | en_US |
| dc.subject | microwave irradiation | en_US |
| dc.subject | [4+1] cycloaddition | en_US |
| dc.subject | imidazo[1,2-a]benzimidazoles | en_US |
| dc.subject | three-component reaction | en_US |
| dc.title | One-Pot, Two-Step Synthesis of Imidazo[1,2-a]benzimidazoles via A Multicomponent [4+1] Cycloaddition Reaction | en_US |
| dc.type | Article | en_US |