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Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database

dc.citation.issue3en_US
dc.citation.volume8en_US
dc.citation.woscount35
dc.contributor.authorTung, Chi-Huaen_US
dc.contributor.authorHuang, Jhang-Weien_US
dc.contributor.authorYang, Jinn-Moonen_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.department生物資訊及系統生物研究所zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.contributor.departmentInstitude of Bioinformatics and Systems Biologyen_US
dc.date.accessioned2014-12-08T15:14:58Z
dc.date.available2014-12-08T15:14:58Z
dc.date.issued2007en_US
dc.description.abstractWe present a novel protein structure database search tool, 3D- BLAST, that is useful for analyzing novel structures and can return a ranked list of alignments. This tool has the features of BLAST ( for example, robust statistical basis, and effective and reliable search capabilities) and employs a kappa-alpha (kappa, alpha) plot derived structural alphabet and a new substitution matrix. 3D- BLAST searches more than 12,000 protein structures in 1.2 s and yields good results in zones with low sequence similarity.en_US
dc.identifier.doi10.1186/gb-2007-8-3-r31en_US
dc.identifier.issn1474-760Xen_US
dc.identifier.journalGENOME BIOLOGYen_US
dc.identifier.urihttp://dx.doi.org/10.1186/gb-2007-8-3-r31en_US
dc.identifier.urihttps://ir.lib.nycu.edu.tw/handle/11536/11253
dc.identifier.wosnumberWOS:000246081600013
dc.language.isoen_USen_US
dc.titleKappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure databaseen_US
dc.typeArticleen_US

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