Synthesis of eburnamine, isoeburnamine, and eburnamonine via a spirocyclic intermediate
| dc.citation.epage | 2770 | en_US |
| dc.citation.issue | 10 | en_US |
| dc.citation.spage | 2764 | en_US |
| dc.citation.volume | 88 | en_US |
| dc.citation.woscount | 6 | |
| dc.contributor.author | Ho, TL | en_US |
| dc.contributor.author | Chen, CK | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:37:06Z | |
| dc.date.available | 2014-12-08T15:37:06Z | |
| dc.date.issued | 2005 | en_US |
| dc.description.abstract | Racemic eburnamonine (1) was synthesized via 6, an intermediate possessing local symmetry. Cleavage of the cyclopentene subunit led to pentacyclic aldehydes 8a/8b which on subsequent borohydride and Wolff-Kishner reductions gave 12. The final steps included a RuCl3-catalyzed periodate oxidation and pyridimum chlorochromate (PCC) oxidation. The penultimate intermediates were racemic eburnamine (2) and racemic isoeburnamine (3). | en_US |
| dc.identifier.doi | 10.1002/hlca.200590216 | en_US |
| dc.identifier.issn | 0018-019X | en_US |
| dc.identifier.journal | HELVETICA CHIMICA ACTA | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1002/hlca.200590216 | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/25464 | |
| dc.identifier.wosnumber | WOS:000233154200020 | |
| dc.language.iso | en_US | en_US |
| dc.title | Synthesis of eburnamine, isoeburnamine, and eburnamonine via a spirocyclic intermediate | en_US |
| dc.type | Article | en_US |