Stereoselective synthesis of 2-isocyanoallopupukeanane

Abstract

[GRAPHICS] A stereoselective synthesis of 2-isocyanoaliopupukeanane (3) in ca, 5% overall yield features an intramolecular Diels-Alder reaction to establish a bridged cydopentane ring to the existing bicyclo[3.2.1]octane unit.