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A sensitive and selective fluorescent sensor for Zinc(II) and its application to living cell imaging

dc.citation.epage725en_US
dc.citation.issueen_US
dc.citation.spage719en_US
dc.citation.volume203en_US
dc.citation.woscount1
dc.contributor.authorLiu, Hao-Mingen_US
dc.contributor.authorVenkatesan, Parthibanen_US
dc.contributor.authorWu, Shu-Paoen_US
dc.contributor.department交大名義發表zh_TW
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentNational Chiao Tung Universityen_US
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.date.accessioned2014-12-08T15:36:46Z
dc.date.available2014-12-08T15:36:46Z
dc.date.issued2014-11-01en_US
dc.description.abstractA new dipyrromethene derivative (DPI) exhibits an enhanced fluorescence in the presence of Zn2+ ions and a high selectivity for Zn2+ ions over competing metal ions in methanol; Ag+, Ca2+, Co2+, Cr3+, Fe2+, Fe3+, Hg2+, Mg2+, Mn2+, Ni2+, and Pb2+ produced only minor changes in the fluorescence of DPI. The binding ratio of the DPI-Zn2+ complexes was determined from a Job plot to be 1:1. The binding constant (K-a) of Zn2+ binding to DPI was found to be 6.12 x 10(4) M-1, with a detection limit of 0.236 mu M. Fluorescence microscopy imaging using RAW264.7 cells showed that DPI could be used as an effective fluorescent probe for detecting Zn2+ in living cells. (C) 2014 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.snb.2014.07.049en_US
dc.identifier.issn0925-4005en_US
dc.identifier.journalSENSORS AND ACTUATORS B-CHEMICALen_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.snb.2014.07.049en_US
dc.identifier.urihttps://ir.lib.nycu.edu.tw/handle/11536/25150
dc.identifier.wosnumberWOS:000341455400095
dc.language.isoen_USen_US
dc.subjectSensorsen_US
dc.subjectZn(II)en_US
dc.subjectFluorescenceen_US
dc.subjectImaging agentsen_US
dc.titleA sensitive and selective fluorescent sensor for Zinc(II) and its application to living cell imagingen_US
dc.typeArticleen_US

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