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Synthesis of calix[4]arenes with four different "lower rim" substituents

dc.citation.epage2679en_US
dc.citation.issue8en_US
dc.citation.spage2673en_US
dc.citation.volume64en_US
dc.citation.woscount37
dc.contributor.authorShu, CMen_US
dc.contributor.authorChung, WSen_US
dc.contributor.authorWu, SHen_US
dc.contributor.authorHo, ZCen_US
dc.contributor.authorLin, LGen_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.date.accessioned2014-12-08T15:46:41Z
dc.date.available2014-12-08T15:46:41Z
dc.date.issued1999-04-16en_US
dc.description.abstractCalix[4]arenes with four different "lower rim" substituents were synthesized following six-step sequences. The first alkyl group (R-1) was introduced using R1X and CH3ONa, and then reaction with R2X and K2CO3 led to the introduction of a second alkyl group (R-2) at the 3-position. Benzoate was introduced as a protecting group at the 1,3-O-disubstituent stage and was removed under basic conditions after the incorporation of the third alkyl group (R-3) With R3X and NaH, The final alkyl group (R-4) was introduced with R4X and NaH to give the chiral title compounds.en_US
dc.identifier.doi10.1021/jo981648len_US
dc.identifier.issn0022-3263en_US
dc.identifier.journalJOURNAL OF ORGANIC CHEMISTRYen_US
dc.identifier.urihttp://dx.doi.org/10.1021/jo981648len_US
dc.identifier.urihttps://ir.lib.nycu.edu.tw/handle/11536/31393
dc.identifier.wosnumberWOS:000079926900013
dc.language.isoen_USen_US
dc.titleSynthesis of calix[4]arenes with four different "lower rim" substituentsen_US
dc.typeArticleen_US

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