Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells
| dc.citation.epage | 390 | en_US |
| dc.citation.issue | en_US | |
| dc.citation.spage | 388 | en_US |
| dc.citation.volume | 113 | en_US |
| dc.citation.woscount | 3 | |
| dc.contributor.author | Yang, Yun-Liang | en_US |
| dc.contributor.author | Wang, Chih-Wei | en_US |
| dc.contributor.author | Chen, Chiung-Tony | en_US |
| dc.contributor.author | Wang, Min-Hsien | en_US |
| dc.contributor.author | Hsiao, Chin-Fu | en_US |
| dc.contributor.author | Lo, Hsiu Juny | en_US |
| dc.contributor.department | 生物科技學系 | zh_TW |
| dc.contributor.department | Department of Biological Science and Technology | en_US |
| dc.date.accessioned | 2014-12-08T15:09:55Z | |
| dc.date.available | 2014-12-08T15:09:55Z | |
| dc.date.issued | 2009-03-01 | en_US |
| dc.description.abstract | Although Candida albicans cph1/cph1 efg1/efg1 mutant cells are not lethal to mice, they proliferated in infected mice instead of simply being cleared by the host immune system. Here, we have shown that the cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by the lethal wild-type Candida albicans cells. Our results further indicate that a second dose of the cph1/cph1 efg1/efg1 mutant did not boost the degree of protection. (c) 2008 The British Mycological Society. Published by Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.doi | 10.1016/j.mycres.2008.11.016 | en_US |
| dc.identifier.issn | 0953-7562 | en_US |
| dc.identifier.journal | MYCOLOGICAL RESEARCH | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1016/j.mycres.2008.11.016 | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/7580 | |
| dc.identifier.wosnumber | WOS:000264693700011 | |
| dc.language.iso | en_US | en_US |
| dc.subject | Candida albicans | en_US |
| dc.subject | Mouse model | en_US |
| dc.subject | Protection | en_US |
| dc.subject | Virulence | en_US |
| dc.title | Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells | en_US |
| dc.type | Article | en_US |