Skeletally Diverse Synthesis of Indole-Fused Diazocine and Diazepine Frameworks by One-Pot, Two-Component Cascade Reaction

dc.citation.epage	319	en_US
dc.citation.spage	316	en_US
dc.citation.volume	18	en_US
dc.citation.woscount	0	en_US
dc.contributor.author	Thikekar, Tushar Ulhas	en_US
dc.contributor.author	Selvaraju, Manikandan	en_US
dc.contributor.author	Sun, Chung-Ming	en_US
dc.contributor.department	應用化學系	zh_TW
dc.contributor.department	Department of Applied Chemistry	en_US
dc.date.accessioned	2016-03-28T00:04:25Z
dc.date.available	2016-03-28T00:04:25Z
dc.date.issued	2016-01-15	en_US
dc.description.abstract	An expeditious and novel strategy has been explored for the synthesis of structurally diverse indole-fused diazocine and diazepine derivatives. A substrate-based diversification approach of methyl-3-aminoindole/indoline benzoates coupled with the Pictet-Spengler reaction and three different reaction cascades furnished indolodiazepine and indoloquinoxalines. The formation of indolodiazocines proceeds through an initial condensation followed by intramolecular alkylation.	en_US
dc.identifier.doi	10.1021/acs.orglett.5b03481	en_US
dc.identifier.issn	1523-7060	en_US
dc.identifier.journal	ORGANIC LETTERS	en_US
dc.identifier.uri	http://dx.doi.org/10.1021/acs.orglett.5b03481	en_US
dc.identifier.uri	https://ir.lib.nycu.edu.tw/handle/11536/129669
dc.identifier.wosnumber	WOS:000368563200043	en_US
dc.language.iso	en_US	en_US
dc.title	Skeletally Diverse Synthesis of Indole-Fused Diazocine and Diazepine Frameworks by One-Pot, Two-Component Cascade Reaction	en_US
dc.type	Article	en_US

Files

Now showing 1 - 1 of 1