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Microwave-assisted benzimidazole cyclization by bismuth chloride

dc.citation.epage1246en_US
dc.citation.issue8en_US
dc.citation.spage1243en_US
dc.citation.volumeen_US
dc.citation.woscount13
dc.contributor.authorSu, YSen_US
dc.contributor.authorSun, CMen_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.date.accessioned2014-12-08T15:19:07Z
dc.date.available2014-12-08T15:19:07Z
dc.date.issued2005-05-17en_US
dc.description.abstractWe have developed a multi-step, microwave-assisted method for the bismuth chloride catalyzed synthesis of 1,2-disubstituted benzimidazoles. Biologically interesting benzimidazoles were readily assembled using a SNAr reaction, reduction, and finally a bismuth(III)-mediated cyclization under microwave irradiation. The desired products were then liberated from the soluble matrix in excellent yield and purity after cleavage. Each step of the synthetic sequence was performed under microwave conditions.en_US
dc.identifier.doi10.1055/s-2005-865240en_US
dc.identifier.issn0936-5214en_US
dc.identifier.journalSYNLETTen_US
dc.identifier.urihttp://dx.doi.org/10.1055/s-2005-865240en_US
dc.identifier.urihttps://ir.lib.nycu.edu.tw/handle/11536/13706
dc.identifier.wosnumberWOS:000229298900006
dc.language.isoen_USen_US
dc.subjectbismuth chlorideen_US
dc.subjectcombinatorial chemistryen_US
dc.subjectliquid-phase methoden_US
dc.subjectmicrowave assisted synthesisen_US
dc.subjectscaffolden_US
dc.titleMicrowave-assisted benzimidazole cyclization by bismuth chlorideen_US
dc.typeArticleen_US

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