Parallel synthesis of amino bis-benzimidazoles by multistep microwave irradiation
| dc.citation.epage | 2604 | en_US |
| dc.citation.issue | 15 | en_US |
| dc.citation.spage | 2601 | en_US |
| dc.citation.volume | 47 | en_US |
| dc.citation.woscount | 17 | |
| dc.contributor.author | Wu, CH | en_US |
| dc.contributor.author | Sun, CM | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:16:51Z | |
| dc.date.available | 2014-12-08T15:16:51Z | |
| dc.date.issued | 2006-04-10 | en_US |
| dc.description.abstract | A multistep liquid phase synthesis of specifically functionalized bis-benzimidazoles is presented by the application of single-mode microwave irradiation technique. The sustained solubilizing power and stability of the PEG-ester derived from the commercially available 4-fluoro-3-nitrobenzoic acid has been successfully carried through 10 steps involving iPSO-SNAr reaction, neutral reduction and acid cyclization. All the steps in this synthetic sequence were assisted by microwave (MW) irradiation. The polymer support was cleaved to release the final head to tail bisbenzimidazoles in an efficient process. (c) 2006 Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.doi | 10.1016/j.tetlet.2006.02.015 | en_US |
| dc.identifier.issn | 0040-4039 | en_US |
| dc.identifier.journal | TETRAHEDRON LETTERS | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1016/j.tetlet.2006.02.015 | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/12384 | |
| dc.identifier.wosnumber | WOS:000236438100031 | |
| dc.language.iso | en_US | en_US |
| dc.title | Parallel synthesis of amino bis-benzimidazoles by multistep microwave irradiation | en_US |
| dc.type | Article | en_US |