Nonparametric multiple test procedures for dose finding
| dc.citation.epage | 1037 | en_US |
| dc.citation.issue | 4 | en_US |
| dc.citation.spage | 1021 | en_US |
| dc.citation.volume | 33 | en_US |
| dc.citation.woscount | 1 | |
| dc.contributor.author | Jan, SL | en_US |
| dc.contributor.author | Shieh, G | en_US |
| dc.contributor.department | 管理科學系 | zh_TW |
| dc.contributor.department | Department of Management Science | en_US |
| dc.date.accessioned | 2014-12-08T15:39:56Z | |
| dc.date.available | 2014-12-08T15:39:56Z | |
| dc.date.issued | 2004 | en_US |
| dc.description.abstract | We consider identifying the minimum effective dose (MED) in a one-way layout, where the MED is defined to be the lowest dose level that is more effective than the zero-dose control. Proposed herein are two rank-based nonparametric step-down closed testing procedures that do not make order assumptions on the dose-response relationship. The corresponding p-value for the estimated MED is computed. A numerical example is given to illustrate the proposed tests. Finally, the results of a Monte Carlo study of the relative error rate and power performances are reported. | en_US |
| dc.identifier.doi | 10.1081/SAC-200040305 | en_US |
| dc.identifier.issn | 0361-0918 | en_US |
| dc.identifier.journal | COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1081/SAC-200040305 | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/27284 | |
| dc.identifier.wosnumber | WOS:000225514900010 | |
| dc.language.iso | en_US | en_US |
| dc.subject | dose-response study | en_US |
| dc.subject | minimum effective dose | en_US |
| dc.subject | one-way layout | en_US |
| dc.subject | step-down closed test | en_US |
| dc.title | Nonparametric multiple test procedures for dose finding | en_US |
| dc.type | Article | en_US |