One-pot formation of fluorescent gamma-lactams having an alpha-phosphorus ylide moiety through three-component alpha(delta ')-Michael reactions of phosphines with an enyne and N-tosyl aldimines
| dc.citation.epage | 170 | en_US |
| dc.citation.issue | 1 | en_US |
| dc.citation.spage | 162 | en_US |
| dc.citation.volume | 12 | en_US |
| dc.citation.woscount | 4 | |
| dc.contributor.author | Lin, Yu-Wei | en_US |
| dc.contributor.author | Deng, Jie-Cheng | en_US |
| dc.contributor.author | Hsieh, You-Zung | en_US |
| dc.contributor.author | Chuang, Shih-Ching | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:34:34Z | |
| dc.date.available | 2014-12-08T15:34:34Z | |
| dc.date.issued | 2014-01-07 | en_US |
| dc.description.abstract | We demonstrate a straightforward synthesis of gamma-lactams possessing an a-phosphorus Aide moiety from assembly of phosphines, N-tosyl aldimines and an enyne through an initial alpha(delta')-attack of phosphines to an enyne in up to 79% yield. The investigated multicomponent reaction tolerates a variety of triaryl-phosphines and electron-poor aldimines to give gamma-lactams in one pot. One of the lactams, with the tri(p-tol)phosphine and 4-cyanophenyl moiety, exhibits fluorescence emission at 447 nm with a quantum yield of 0.11. | en_US |
| dc.identifier.doi | 10.1039/c3ob41811a | en_US |
| dc.identifier.issn | 1477-0520 | en_US |
| dc.identifier.journal | ORGANIC & BIOMOLECULAR CHEMISTRY | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1039/c3ob41811a | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/23606 | |
| dc.identifier.wosnumber | WOS:000329551100019 | |
| dc.language.iso | en_US | en_US |
| dc.title | One-pot formation of fluorescent gamma-lactams having an alpha-phosphorus ylide moiety through three-component alpha(delta ')-Michael reactions of phosphines with an enyne and N-tosyl aldimines | en_US |
| dc.type | Article | en_US |