A synthesis of 6-myoporol
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DOI
10.1021/np960704f
Abstract
An approach to (+/-)-6-myoporol (1) featured stereocontrol by equilibration of 2,6-disubstituted cyclohexanones to mainly the cis isomer. The synthesis was completed by reaction of a lactone intermediate with 3-lithiofuran, Mitsunobu reaction, and hydrolysis.