Regioselective Piperidine-Catalyzed Tandem Imination-Isocyanate Annulation to Fused Tricyclic Triazines
| dc.citation.epage | 249 | en_US |
| dc.citation.issue | 5 | en_US |
| dc.citation.spage | 244 | en_US |
| dc.citation.volume | 16 | en_US |
| dc.citation.woscount | 1 | |
| dc.contributor.author | Barve, Indrajeet J. | en_US |
| dc.contributor.author | Chen, Chih-Hau | en_US |
| dc.contributor.author | Kao, Chih-Hsien | en_US |
| dc.contributor.author | Sun, Chung-Ming | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:36:06Z | |
| dc.date.available | 2014-12-08T15:36:06Z | |
| dc.date.issued | 2014-05-01 | en_US |
| dc.description.abstract | A novel tandem imination-isocyanate-mediated annulation was explored. Ionic liquid-immobilized 2-aminobenzimidazoles react sequentially with aldehydes and isocyanates to give highly functionalized benzimidazole-embedded triazines. The second-stage transformation revealed that the formation of triazinone functionality is entirely regioselective to allow rapid assembly of biologically interesting tricyclic skeletons. In conjunction with the application of microwave irradiation and IL support, this method provides an efficient route to access substituted benzoimidazotriazines. | en_US |
| dc.identifier.doi | 10.1021/co400159z | en_US |
| dc.identifier.issn | 2156-8952 | en_US |
| dc.identifier.journal | ACS COMBINATORIAL SCIENCE | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1021/co400159z | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/24454 | |
| dc.identifier.wosnumber | WOS:000335940000008 | |
| dc.language.iso | en_US | en_US |
| dc.subject | tandem reaction | en_US |
| dc.subject | imination | en_US |
| dc.subject | isocyanate-mediated annulation | en_US |
| dc.subject | benzoimidazotriazine | en_US |
| dc.subject | ionic liquid | en_US |
| dc.subject | microwave | en_US |
| dc.title | Regioselective Piperidine-Catalyzed Tandem Imination-Isocyanate Annulation to Fused Tricyclic Triazines | en_US |
| dc.type | Article | en_US |