Automated Solution-Phase Synthesis of Oligosaccharides via Iterative Electrochemical Assembly of Thioglycosides
| dc.citation.epage | 4523 | en_US |
| dc.citation.issue | 17 | en_US |
| dc.citation.spage | 4520 | en_US |
| dc.citation.volume | 15 | en_US |
| dc.citation.woscount | 6 | |
| dc.contributor.author | Nokami, Toshiki | en_US |
| dc.contributor.author | Hayashi, Ryutaro | en_US |
| dc.contributor.author | Saigusa, Yoshihiro | en_US |
| dc.contributor.author | Shimizu, Akihiro | en_US |
| dc.contributor.author | Liu, Chih-Yueh | en_US |
| dc.contributor.author | Mong, Kwok-Kong Tony | en_US |
| dc.contributor.author | Yoshida, Jun-ichi | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:34:16Z | |
| dc.date.available | 2014-12-08T15:34:16Z | |
| dc.date.issued | 2013-09-06 | en_US |
| dc.description.abstract | A new iterative one-pot sequential method for the solution-phase synthesis of oligosaccharides has been devised on the basis of the electrochemical oxidation of a propagating thioglycoside terminus to generate the corresponding triflate, followed by the reaction with a thioglycoside building block having a free hydroxyl group. A practical automated synthesizer was developed for the method and was effectively used for assembling up to six thioglycoside building blocks to synthesize partial structures of poly-beta-D-(1-6)-N-acetylglucosamine. | en_US |
| dc.identifier.doi | 10.1021/ol402034g | en_US |
| dc.identifier.issn | 1523-7060 | en_US |
| dc.identifier.journal | ORGANIC LETTERS | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1021/ol402034g | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/23482 | |
| dc.identifier.wosnumber | WOS:000328864800063 | |
| dc.language.iso | en_US | en_US |
| dc.title | Automated Solution-Phase Synthesis of Oligosaccharides via Iterative Electrochemical Assembly of Thioglycosides | en_US |
| dc.type | Article | en_US |