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A pyrene-based highly selective turn-on fluorescent sensor for copper(II) ions and its application in living cell imaging

dc.citation.epage748en_US
dc.citation.issueen_US
dc.citation.spage743en_US
dc.citation.volume181en_US
dc.citation.woscount10
dc.contributor.authorWang, Hsuan-Fuen_US
dc.contributor.authorWu, Shu-Paoen_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.date.accessioned2014-12-08T15:30:13Z
dc.date.available2014-12-08T15:30:13Z
dc.date.issued2013-05-01en_US
dc.description.abstractA new pyrene derivative (1) containing a benzothiazolenhydrazone moiety exhibited high selectivity for Cu2+ detection. In the presence of Cu2+, chemosensor 1 provided significant fluorescence enhancement, while Ag+, Ca2+, Cd2+, Co2+, Fe2+, Fe3+, Hg2+, K+, Mg2+, Mn2+, Ni2+, Pb2+, and Zn2+ metal ions produced only minor changes in fluorescence intensity. The association constant (K-a) for Cu2+ binding to 1 had a value of 5.00 x 10(8) M-2. The maximum fluorescence enhancement induced by Cu2+ binding to the chemosensor was observed over the range pH 2-8.5. Our fluorescence microscopy experiments demonstrate that chemosensor 1 may have application as a fluorescent probe for detecting Cu2+ in living cells. (c) 2013 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.snb.2013.01.054en_US
dc.identifier.issn0925-4005en_US
dc.identifier.journalSENSORS AND ACTUATORS B-CHEMICALen_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.snb.2013.01.054en_US
dc.identifier.urihttps://ir.lib.nycu.edu.tw/handle/11536/21651
dc.identifier.wosnumberWOS:000317941100102
dc.language.isoen_USen_US
dc.subjectSensorsen_US
dc.subjectCopperen_US
dc.subjectPyreneen_US
dc.subjectImaging agentsen_US
dc.titleA pyrene-based highly selective turn-on fluorescent sensor for copper(II) ions and its application in living cell imagingen_US
dc.typeArticleen_US

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