A concise route to racemic anatoxin a from cycloocta-1,5-diene
| dc.citation.epage | 137 | en_US |
| dc.citation.issue | 1 | en_US |
| dc.citation.spage | 134 | en_US |
| dc.citation.volume | 89 | en_US |
| dc.citation.woscount | 1 | |
| dc.contributor.author | Ho, TL | en_US |
| dc.contributor.author | Zinurova, E | en_US |
| dc.contributor.department | 應用化學系 | zh_TW |
| dc.contributor.department | Department of Applied Chemistry | en_US |
| dc.date.accessioned | 2014-12-08T15:17:44Z | |
| dc.date.available | 2014-12-08T15:17:44Z | |
| dc.date.issued | 2006 | en_US |
| dc.description.abstract | The synthesis of racemic anatoxin a (1a) from cycloocta-1,5-diene via its 1:1 cycloadduct with N-chlorosulfonyl isocyanate is described. The N-unsubstituted beta-lactam 2b was converted to a beta-amino ester 3 which was then submitted to a Pd-catalyzed cyclization to afford the conjugated ester 4a. The N-tosyl derivative 4b was then elaborated into N-tosylanatoxin a (1b) via a Weinreb amide. | en_US |
| dc.identifier.doi | 10.1002/hlca.200690005 | en_US |
| dc.identifier.issn | 0018-019X | en_US |
| dc.identifier.journal | HELVETICA CHIMICA ACTA | en_US |
| dc.identifier.uri | http://dx.doi.org/10.1002/hlca.200690005 | en_US |
| dc.identifier.uri | https://ir.lib.nycu.edu.tw/handle/11536/12885 | |
| dc.identifier.wosnumber | WOS:000234988100015 | |
| dc.language.iso | en_US | en_US |
| dc.title | A concise route to racemic anatoxin a from cycloocta-1,5-diene | en_US |
| dc.type | Article | en_US |