Browsing by Issue Date, starting with "2015-11-04"

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Multitheragnostic Multi-GNRs Crystal-Seeded Magnetic Nanoseaurchin for Enhanced In Vivo Mesenchymal-Stem-Cell Homing, Multimodal Imaging, and Stroke Therapy
(2015-11-04)
Chen, Po-Jung
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Kang, Yi-Da
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Lin, Chen-Huan
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Chen, San-Yuan
;
Hsieh, Chia-Hung
A multifunctional nanoseaurchin probe in which mesoporous silica nanobeads with iron oxide nanoparticles embedded and multi-gold nanorods crystal-seeded are fabricated and labeled with umbilical cord mesenchymal stem cells through endocytosis. This nanoplatform enables efficient magnetic remote-controlled guiding for stem cell homing, and provides dual modalities of photoacoustic imaging and magnetic resonance imaging for in situ tracking and long-term monitoring to achieve therapeutic efficacy.
Amoeboid motion in confined geometry
(2015-11-04)
Wu, Hao
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Thiebaud, M.
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Hu, W. -F.
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Farutin, A.
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Rafai, S.
Many eukaryotic cells undergo frequent shape changes (described as amoeboid motion) that enable them to move forward. We investigate the effect of confinement on a minimal model of amoeboid swimmer. A complex picture emerges: (i) The swimmer's nature (i.e., either pusher or puller) can be modified by confinement, thus suggesting that this is not an intrinsic property of the swimmer. This swimming nature transition stems from intricate internal degrees of freedom of membrane deformation. (ii) The swimming speed might increase with increasing confinement before decreasing again for stronger confinements. (iii) A straight amoeoboid swimmer's trajectory in the channel can become unstable, and ample lateral excursions of the swimmer prevail. This happens for both pusher- and puller-type swimmers. For weak confinement, these excursions are symmetric, while they become asymmetric at stronger confinement, whereby the swimmer is located closer to one of the two walls. In this study, we combine numerical and theoretical analyses.
Multilayer MoS2 prepared by one-time and repeated chemical vapor depositions: anomalous Raman shifts and transistors with high ON/OFF ratio
(2015-11-04)
Wu, Chong-Rong
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Chang, Xiang-Rui
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Chang, Shu-Wei
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Chang, Chung-En
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Wu, Chao-Hsin
We show that multilayer molybdenum disulfide (MoS2) grown with the chemical vapor deposition (CVD) may exhibit quite distinct behaviors of Raman shifts from those of exfoliated ones. The anomalous Raman shifts depend on CVD growth modes and are attributed to the modified dielectric screening and interlayer coupling of MoS2 in various growth conditions. With repeated CVD growths, we demonstrated the precise control over the layer number of MoS2. A decently large drain current, high ON/OFF ratio of 10(5), and enhanced field-effect mobility can be achieved in transistors fabricated on the six-layer MoS2.
A real-time monitoring system for soluble gas pollutants and it's application for determining the control efficiency of packed towers
(2015-11-05)
Chien, Chih-Liang
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Iswara, Aditya Prana
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Liou, Yi-Ling
;
Wang, Bing-Tsai
;
Chang, Jui-Chiao
This study used a parallel-plate wet denuder coupled with an ion chromatograph (PPWD-IC) to monitor soluble gas pollutants in the exhaust stack and investigate the removal efficiency of packed towers. Gas pollutant concentrations measured by the PPWD-IC system were first validated with those obtained by a manual porous metal denuder sampler (PDS) as the reference sampler. The measured concentrations of the PPWD-IC system are in good agreement with those of the PDS with the coefficient of determination (R-2) greater than 0.93. The PPWD-IC system was then used to determine the removal efficiency of packed towers in high-tech factories. Results show that the PPWD-IC system is able to monitor multiple high-concentration gas pollutants semi-continuously, such as HF, HCl, HNO2, HNO3, CH3COOH, and NH3, in the exhaust stack with a temporal resolution of 20 min. The PPWD-IC system was employed to test the gas removal efficiency of a new honeycomb wet scrubber in an optoelectronic factory. The removal efficiency of the wet scrubber equipped with the honeycomb module at the liquid-to-gas ratio of 18.5 L/m(3) is shown to be close to 100% for HF (112.4-448.4 ppbv) and CH3COOH (696.3-6537.0 ppbv) and 99% for HCI (3394,9-10794.5 ppbv), respectively. (C) 2015 Elsevier B.V. All rights reserved.
Effects of post-annealing on the structural and nanomechanical properties of sputter-deposited FePd thin films
(2015-11-05)
Jian, S. -R.
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Chang, H. -W.
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Wang, Y. -W.
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Yeh, H. -H.
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Juang, J. -Y.
The effects of post-annealing on the microstructures, surface morphologies and nanomechanical characteristics of FePd thin films are investigated by means of X-ray diffraction (XRD), atomic force microscopy (AFM), transmission electron microscopy (TEM) and nanoindentation techniques. The FePd thin films were deposited on the glass substrates at room temperature by magnetron sputtering system. Post-annealing was carried out at 500, 600 and 700 degrees C, respectively, resulting in progressive increase of the average grain size and surface roughness of FePd thin films, as well as the improved film crystallinity. XRD results show that FePd thin films are predominantly (111)-oriented, indicating a well-ordered microstructure. The hardness and Young\'s modulus of FePd thin films measured by a Berkovich nanoindenter operated with the continuous contact stiffness measurements (CSM) option indicated that both mechanical properties are decreased with increasing the annealing temperature. Furthermore, the relationship between the hardness and films grain size appears to follow closely with the Hall-Petch equation. (C) 2015 Elsevier B.V. All rights reserved.
交大e-News第197期-交大研發八軸飛行器結合遙控App 農業監控可望實現
(2015-11-05)
國立交通大學秘書室
;
Secretariat
ACTIVE GUARD RING STRUCTURE TO IMPROVE LATCH-UP IMMUNITY
(2015-11-05)
KER MING-DOU
;
TSAI HUI-WEN
An active guard ring structure is provided, which is applicable to improving latch-up immunity during the latch-up current test (I-test). The proposed active guard ring structure comprises an I/O circuit and an active protection circuit, wherein the I/O circuit receives a trigger current via an input pad and generates a corresponding bulk current since being triggered. The active protection circuit, connected between the I/O circuit and a core circuit, detects whether the trigger current is a positive or negative current pulse. When an intensity of the trigger current is larger than a threshold value, the active protection circuit controls the I/O circuit to provide a sink or compensation current so as to neutralize the bulk current and to reduce the net current flowing into or sourced from the core circuit, thereby increasing the latch-up resistance and immunity of the core circuit.
PORTABLE NONINVASIVE INSPECTION DEVICE
(2015-11-05)
OU-YANG Mang
;
HUANG Ting-Wei
;
YANG Chin-Siang
;
HSIEH Yao-Fang
;
LI Sing-Tsung
The present invention discloses a portable noninvasive inspection device, which comprises a light source illuminates a target to generate an optical inspection signal; a probe head provides an optical path for said light source to receive said optical inspection signal; at least one switched filter module arranged in the optical path, allowing the optical inspection signal to pass there through to generate a corresponding spectral signal; and an image sensor arranged behind the switched filter module, receiving the spectral signal and generating a spectral image. The spectral image can be transmitted to an external device, wherefrom the user can use the spectral image to examine the target in further detail. The present invention features a rotary-type or movable-type switched filter module, which facilitates the user to switch filters easily during optical inspection and expands the application of the present invention.
Multicomponent Synthesis of Functionalized Tetrahydroacridinones: Insights into a Mechanistic Route
(2015-11-06)
Chung, Tsai-Wen
;
Narhe, Bharat D.
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Lin, Chun-Cheng
;
Sun, Chung-Ming
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應用化學系
A mechanistic study of three-component reactions of various aromatic amines with a number of aldehydes and 1,3-diones was achieved. The unprecedented reaction involved a nucleophilic attack of an aromatic amine on the in situ generated Michael adduct intermediate followed by six-electron ring cyclizations. It is contrary to the common belief that advocates involvement of coupling reactions between a Knoevenagel adduct and an aromatic amine to deliver substituted tetrahydroacridinones.
Enhanced critical current density in the pressure-induced magnetic state of the high-temperature superconductor FeSe
(2015-11-09)
Jung, Soon-Gil
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Kang, Ji-Hoon
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Park, Eunsung
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Lee, Sangyun
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Lin, Jiunn-Yuan
We investigate the relation of the critical current density (J(c)) and the remarkably increased superconducting transition temperature (T-c) for the FeSe single crystals under pressures up to 2.43 GPa, where the T-c is increased by similar to 8 K/GPa. The critical current density corresponding to the free flux flow is monotonically enhanced by pressure which is due to the increase in T-c, whereas the depinning critical current density at which the vortex starts to move is more influenced by the pressure-induced magnetic state compared to the increase of T-c. Unlike other high-T-c superconductors, FeSe is not magnetic, but superconducting at ambient pressure. Above a critical pressure where magnetic state is induced and coexists with superconductivity, the depinning Jc abruptly increases even though the increase of the zero-resistivity T-c is negligible, directly indicating that the flux pinning property compared to the T-c enhancement is a more crucial factor for an achievement of a large J(c). In addition, the sharp increase in J(c) in the coexisting superconducting phase of FeSe demonstrates that vortices can be effectively trapped by the competing antiferromagnetic order, even though its antagonistic nature against superconductivity is well documented. These results provide new guidance toward technological applications of high-temperature superconductors.
Topological control of nitric oxide secretion by tantalum oxide nanodot arrays
(2015-11-09)
Dhawan, Udesh
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Lee, Chia Hui
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Huang, Chun-Chung
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Chu, Ying Hao
;
Huang, Guewha S.
Background: Nitric oxide (NO) plays a very important role in the cardiovascular system as a major secondary messenger in signaling pathway. Its concentration regulates most of the important physiological indexes including the systemic blood pressure, blood flow, regional vascular tone and other cardiac functions. The effect of nanotopography on the NO secretion in cardiomyocytes has not been elucidated before. In this study, we report how the nanotopography can modulate the secretion profile of NO and attempt to elucidate the genetic pathways responsible for the same by using Tantalum Oxide nanodot arrays ranging from 10 to 200 nm. A series of nanodot arrays were fabricated with dot diameter ranging from 10 to 200 nm. Temporal NO release of cardiomyocytes was quantified when grown on different surfaces. Quantitative RT-PCR and Western blot were performed to verify the genetic pathways of NO release. Results: After hours 24 of cell seeding, NO release was slowly enhanced by the increase of dot diameter from 10 nm up to 50 nm, mildly enhanced to a medium level at 100 nm, and increase rapidly to a high level at 200 nm. The temporal enhancement of NO release dropped dramatically on day 3. On day 5, a topology-dependent profile was established that maximized at 50 nm and dropped to control level at 200 nm. The NO releasing profile was closely associated with the expression patterns of genes associated with Endothelial nitric oxide synthase (eNOS) pathway [GPCR, PI3K, Akt, Bad, Bcl-2, NF kappa B(p65), eNOS], but less associated with Inducible nitric oxide synthase (iNOS) pathway (TNF-alpha, ILK, Akt, I kappa Ba, NF kappa B, iNOS). Western blotting of Akt, eNOS, iNOS, and NF kappa B further validated that eNOS pathway was modulated by nanotopology. Conclusions: Based on the findings of the present study, 50, 100 nm can serve as the suitable nanotopography patterns for cardiac implant surface design. These two nanodot arrays promote NO secretion and can also promote the vascular smooth muscle relaxation. The results of this study can improve the heart stent design in the medical treatments.
Spontaneous orientation-tuning driven by the strain variation in self-assembled ZnO-SrRuO3 heteroepitaxy
(2015-11-09)
Zhu, Yuanmin
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Chang, Wei Sea
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Yu, Rong
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Liu, Ruirui
;
Wei, Tzu-Chiao
Heteroepitaxial ZnO and SrRuO3 were grown on SrTiO3 (111) substrates and formed a self-assembled wurtzite-perovskite nanostructure. Spontaneous orientation-tuning of the SrRuO3 pillars was observed, with the growth direction changing from [111](SRO) to [011](SRO) as the film thickness increased, which is attributed to a misfit strain transition from the biaxial strain imposed by the SrTiO3 substrate to the vertical strain provided by the ZnO matrix. The [011]-SrRuO3 and [0001]-ZnO combination presents a favorable matching in the nanocomposite films, resulting in higher charge carrier mobility. This vertically integrated configuration and regulation on the crystallographic orientations are expected to be employed in designing multi-functional nanocomposite systems for applications in electronic devices. (C) 2015 AIP Publishing LLC.
Gender-Related Effect in Oxygenation Dynamics by Using Far-Infrared Intervention with Near-Infrared Spectroscopy Measurement: A Gender Differences Controlled Trial
(2015-11-10)
Kao, Wei-Lung
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Sun, Chia-Wei
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光電工程學系
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Department of Photonics
Many studies have indicated the microcirculation can directly respond to disease-related symptoms. However, the capacity of microcirculation would vary due to the gender differences. Near-infrared spectroscopy (NIRS) is a noninvasive technique to monitor tissue oxygenation dynamics. In this study, the far-infrared (FIR) source was used for physiological intervention of microcirculation. The experimental results show that the nature difference of oxygenation status exists between male and female during FIR irradiation. Therefore, we suggest the NIRS-based assessment should be calibrated with the gender-related effect for clinical diagnosis of peripheral arterial disease.
單晶銅、其製備方法及包含其之基板
(2015-11-11)
陳智
;
杜經寧
;
呂佳凌
一種單晶銅，該單晶銅具有[100]方向，且體積係介於0.1~4.0×106 μm3 間以及厚度係介於0.1~50μm。
具有優選排列方向之金膜、其製備方法、及包含其之接合結構
(2015-11-11)
陳智
;
邱韋嵐
一種具有優選排列方向之金膜，該金膜係包括互相連接之複數個金晶粒，其中，至少50%以上之該些金晶粒係由複數個奈米雙晶金晶粒所組成，且該奈米雙晶金晶粒係由複數個奈米雙晶金沿著[111]晶軸方向堆疊而成，而該奈米雙晶金晶粒之直徑係0.1~10μm。
半導體元件製造方法
(2015-11-11)
劉柏村
;
鄧立峯
;
羅婉柔
;
李耀仁
一種使用微波退火程序的半導體元件製造方法，用以增強一半導體元件之效能，該製造方法至少包含下列步驟：形成一閘極層於一基板上；形成一閘極絕緣層於該閘極層上；形成一主動層於該閘極絕緣層上，且該主動層係由一微波吸收材料所組成，其中該微波吸收材料係由一金屬氧化物、一金屬氮化物以及一金屬氮氧化物群組中所選出；定義一源/汲極於該主動層上，以形成該半導體元件；以及進行一微波退火程序。
鑽石薄膜成長方法
(2015-11-11)
張立
;
陳昱長
;
陳致宇
一種鑽石薄膜成長方法，係包含下列步驟：提供一底板；藉由一磊晶步驟形成一異質基板於該底板上，其中該異質基板係由多個晶粒長成，且利用該磊晶步驟於該異質基板之一上表面之該多個晶粒之接合處形成不規則的多個微凹槽；提供多個鑽石核種嵌入該多個微凹槽；以及沉積一鑽石薄膜於該異質基板之該上表面。
單級閘極驅動電路之多輸出設計
(2015-11-11)
劉柏村
;
鄭光廷
;
張哲豪
;
周凱茹
;
吳哲耀
一種單級閘極驅動電路之多輸出設計，該單級閘極驅動電路具有多個掃描電路，其包含：一第一掃描電路，其包含：一設定單元，接收一起始訊號，產生一控制訊號；一驅動單元，耦接該設定單元，接收該控制訊號及一第一時脈訊號，該控制訊號及該第一時脈訊號使該驅動單元產生一第一掃描訊號，該驅動單元依據該第一時脈訊號驅動該第一掃描訊號提升至一第一準位，該驅動單元依據該第一時脈訊號驅動該第一掃描訊號降低至一第二準位，該第一準位高於該第二準位；及一第二掃描電路，耦接該第一掃描電路，接收該第一掃描訊號及一第二時脈訊號，該第二掃描電路依據該第一掃描訊號及該第二時脈訊號產生一第二掃描訊號；其中，該單級閘極驅動電路輸出該第一掃描訊號及該第二掃描訊號至複數像素，控制該些像素。
製備有機發光二極體之方法及其裝置
(2015-11-11)
許千樹
;
孟心飛
;
洪勝富
;
冉曉雯
;
曾信榮
一種製備有機發光二極體之方法，係包括下列步驟：提供一基板；於該基板上注佈由有機分子溶解於溶劑中所得之有機分子溶液；藉由刮刀將該有機分子溶液塗佈於該基板表面，以形成濕膜層；於形成該濕膜層後之10秒內，旋轉該基板；以及加熱該濕膜層以去除該溶劑而形成有機分子薄膜。
Guest Editorial for the 13th Asia Pacific Bioinformatics Conference
(2015-11-12)
Huang, Hsien-Da
;
Chen, Yi-Ping Phoebe
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生物資訊及系統生物研究所
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Institude of Bioinformatics and Systems Biology