具生物反餽機制之智慧型長時睡眠監測系統---總計畫(I)

Abstract

人類一生中有三分之一的時間在睡眠中度過，除了心理壓力與生理睡眠 疾病導致睡眠品質不良產生的生理與心理影響外，嬰兒猝死症候群亦常在 睡眠中發生。目前有關睡眠品質與障礙之診斷必須在特定醫院的睡眠中心 進行，所使用之睡眠多重生理監測儀（PolySomnoGraphy，簡稱PSG）必須 黏貼大量的腦波電極、心電圖電極、肌電電極、血氧計等，往往對受測者 的睡眠造成影響，無法準確記錄受測者之真正睡眠狀態。有鑑於此，本計 畫擬研發新型「長時睡眠監測系統」，結合學術單位與醫療單位，共同發 展微小化平台系統的電子元件、完成晶片設計與多重生理訊號之資料探 勘，除了使得可能患有呼吸睡眠中止症的病患能經由較輕便之監測儀器及 早發現病症，在針對嬰幼兒睡眠狀態之照護，研究團隊也希望達到無論是 在醫院或居家，皆能藉此「具生物反饋機制之智慧型長時睡眠監測系統」 即時發現異常狀態並發出警報，使醫護人員或家長能儘速採取正確之照護 行動以降低嬰兒猝死之機率

Sleeping disorder and sleep apnea are common syndromes in modern life. About six hundred thousands adults are the patients with sleep apnea in Taiwan. Also, there are tens of infants was diagnosed as death-on-arrival each year in major hospitals due to sudden infant death syndrome. To avoid such tragically situations, this project proposed to design an intelligent long-time sleep-monitoring system with bio-feedback mechanisms and its corresponding integrated circuits and software. The proposed system contains: sensor and analog front-end circuitries, real-time multi-stream physiological signalprocessor, lossless error correction codes for physiological signal storage, and polysomnographic data mining technology, which will be delivered by different sub-projects. With integration of above technology, a miniaturized multi-stream physiological signal recording and reacting system is proposed, which can be utilized as polysomnography or other clinical devices. It’s labeling and analysis abilities are utilized in diagnosing sleep scoring, sleep apnea, etc. Furthermore, the feed-back stimulation or alarm from the on-line monitoring can provides the functionality to prevent sudden infant death and other syndromes. The propose device can be widely used in emergency rooms, intensive care units, and other long-term care units which is useful to provide in time clinical care and reduce the loading of health care staffs.