Parallel synthesis of amino bis-benzimidazoles by multistep microwave irradiation

doi:10.1016/j.tetlet.2006.02.015

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DC Field	Value	Language
dc.contributor.author	Wu, CH	en_US
dc.contributor.author	Sun, CM	en_US
dc.date.accessioned	2014-12-08T15:16:51Z	-
dc.date.available	2014-12-08T15:16:51Z	-
dc.date.issued	2006-04-10	en_US
dc.identifier.issn	0040-4039	en_US
dc.identifier.uri	http://dx.doi.org/10.1016/j.tetlet.2006.02.015	en_US
dc.identifier.uri	http://hdl.handle.net/11536/12384	-
dc.description.abstract	A multistep liquid phase synthesis of specifically functionalized bis-benzimidazoles is presented by the application of single-mode microwave irradiation technique. The sustained solubilizing power and stability of the PEG-ester derived from the commercially available 4-fluoro-3-nitrobenzoic acid has been successfully carried through 10 steps involving iPSO-SNAr reaction, neutral reduction and acid cyclization. All the steps in this synthetic sequence were assisted by microwave (MW) irradiation. The polymer support was cleaved to release the final head to tail bisbenzimidazoles in an efficient process. (c) 2006 Elsevier Ltd. All rights reserved.	en_US
dc.language.iso	en_US	en_US
dc.title	Parallel synthesis of amino bis-benzimidazoles by multistep microwave irradiation	en_US
dc.type	Article	en_US
dc.identifier.doi	10.1016/j.tetlet.2006.02.015	en_US
dc.identifier.journal	TETRAHEDRON LETTERS	en_US
dc.citation.volume	47	en_US
dc.citation.issue	15	en_US
dc.citation.spage	2601	en_US
dc.citation.epage	2604	en_US
dc.contributor.department	應用化學系	zh_TW
dc.contributor.department	Department of Applied Chemistry	en_US
dc.identifier.wosnumber	WOS:000236438100031	-
dc.citation.woscount	17	-
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