標題: | Nickel-catalysed para-CH activation of pyridine with switchable regioselective hydroheteroarylation of allylarenes |
作者: | Lee, Wei-Chih Chen, Chien-Hung Liu, Cheng-Yuan Yu, Ming-Shiuan Lin, Yung-Huei Ong, Tiow-Gan 應用化學系 Department of Applied Chemistry |
公開日期: | 1-一月-2015 |
摘要: | para-CH activation of pyridine with allylbenzene is described by Ni/Al cooperative catalysis in combination with a bulkier NHC ligand and a Lewis acid, leading to linear hydroheteroarylation products. Interestingly, the branch selectivity can be achieved by using the combination of a less sterically hindered amino-NHC ligand and AlMe3 through tandem reaction of facile alkene isomerization followed by a slow CH bond activation process. |
URI: | http://dx.doi.org/10.1039/c5cc07455j http://hdl.handle.net/11536/129599 |
ISSN: | 1359-7345 |
DOI: | 10.1039/c5cc07455j |
期刊: | CHEMICAL COMMUNICATIONS |
Volume: | 51 |
Issue: | 96 |
起始頁: | 17104 |
結束頁: | 17107 |
顯示於類別: | 期刊論文 |