標題: Portable LED-induced autofluorescence imager with a probe of L shape for oral cancer diagnosis
作者: Huang, Ting-Wei
Lee, Yu-Cheng
Cheng, Nai-Lun
Yan, Yung-Jhe
Chiang, Hou-Chi
Chiou, Jin-Chern
Mang Ou-Yang
分子醫學與生物工程研究所
電機工程學系
電控工程研究所
Institute of Molecular Medicine and Bioengineering
Department of Electrical and Computer Engineering
Institute of Electrical and Control Engineering
關鍵字: autofluorescence;LED;oral cancer;probe;light spots
公開日期: 1-Jan-2015
摘要: The difference of spectral distribution between lesions of epithelial cells and normal cells after excited fluorescence is one of methods for the cancer diagnosis. In our previous work, we developed a portable LED Induced autofluorescence (LIAF) imager contained the multiple wavelength of LED excitation light and multiple filters to capture ex-vivo oral tissue autofluorescence images. Our portable system for detection of oral cancer has a probe in front of the lens for fixing the object distance. The shape of the probe is cone, and it is not convenient for doctor to capture the oral image under an appropriate view angle in front of the probe. Therefore, a probe of L shape containing a mirror is proposed for doctors to capture the images with the right angles, and the subjects do not need to open their mouse constrainedly. Besides, a glass plate is placed in probe to prevent the liquid entering in the body, but the light reflected from the glass plate directly causes the light spots inside the images. We set the glass plate in front of LED to avoiding the light spots. When the distance between the glasses plate and the LED model plane is less than the critical value, then we can prevent the light spots caused from the glasses plate. The experiments show that the image captured with the new probe that the glasses plate placed in the back-end of the probe has no light spots inside the image.
URI: http://dx.doi.org/10.1117/12.2187176
http://hdl.handle.net/11536/129751
ISBN: 978-1-62841-760-9
ISSN: 0277-786X
DOI: 10.1117/12.2187176
期刊: MEDICAL APPLICATIONS OF RADIATION DETECTORS V
Volume: 9594
起始頁: 0
結束頁: 0
Appears in Collections:Conferences Paper


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