標題: Functionalized graphene nanocomposites for enhancing photothermal therapy in tumor treatment
作者: Chen, Yu-Wei
Su, Yu-Lin
Hu, Shang-Hsiu
Chen, San-Yuan
材料科學與工程學系
Department of Materials Science and Engineering
關鍵字: Graphene;Photothermal therapy;Composites;Drug delivery;Tumor therapy
公開日期: 1-Oct-2016
摘要: Graphene and its derivatives have unique physical and chemical properties that make them promising vehicles for photothermal therapy (PTT)-based cancer treatment. With intrinsic near-infrared (NIR) absorption properties, graphene-based nanomaterials can be used for PTT and other therapeutics, particularly in combination therapy, to provide successful thermal ablation of cancer cells. In the recent years, advances in graphene-based PTT have produced efficient and efficacious tumor inhibition via nanomaterial structural design and different functionalizations of graphene-derived nanocomposites. Graphene-based nanosystems exhibit multifunctional properties that are useful for PTT applications including enhancement of multimodalities, guided imaging, enhanced chemotherapy and low-power efficient PTT for optimum therapeutic efficiency. Therefore, in this review, we address critical issues and future aspects of PTT-based combination therapy. (C) 2016 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.addr.2016.05.022
http://hdl.handle.net/11536/132653
ISSN: 0169-409X
DOI: 10.1016/j.addr.2016.05.022
期刊: ADVANCED DRUG DELIVERY REVIEWS
Volume: 105
起始頁: 190
結束頁: 204
Appears in Collections:Articles