標題: Increased risk of sudden sensorineural hearing loss in patients with depressive disorders: population-based cohort study
作者: Lin, C-S
Lin, Y-S
Liu, C-F
Weng, S-F
Lin, C.
Lin, B-S
影像與生醫光電研究所
Institute of Imaging and Biomedical Photonics
關鍵字: Hearing Loss;Sudden;Depressive Disorder
公開日期: Jan-2016
摘要: Objectives: To evaluate the incidence rates and risk of sudden sensorineural hearing loss among patients with depressive disorders. Method: Data for 27 547 patients with newly diagnosed depressive disorders and 27 547 subjects without depressive disorders between 2001 and 2008 were yielded from the Taiwan National Health Insurance Research Database. Sudden sensorineural hearing loss incidence at the end of 2011 was determined. Cumulative incidence and adjusted hazard ratio were computed. Results: Sudden sensorineural hearing loss incidence was 1.45 times higher in the depressive disorders group compared to the non-depressive disorders group (p = 0.0041), with an adjusted hazard ratio of 1.460. A significant increased risk of developing sudden sensorineural hearing loss was noted in patients with diabetes mellitus, chronic kidney disease and hyperlipidaemia (p < 0.05). Conclusion: The results suggest an increased risk of developing sudden sensorineural hearing loss in patients with depressive disorders. Co-morbidities such as diabetes mellitus, chronic kidney disease and hyperlipidaemia significantly aggravated the risk. Depressive disorders might be considered a risk factor for sudden sensorineural hearing loss. It remains to be seen whether control of depressive disorders can decrease the incidence of sudden sensorineural hearing loss in patients with depressive disorders.
URI: http://dx.doi.org/10.1017/S0022215115002960
http://hdl.handle.net/11536/133007
ISSN: 0022-2151
DOI: 10.1017/S0022215115002960
期刊: JOURNAL OF LARYNGOLOGY AND OTOLOGY
Volume: 130
Issue: 1
起始頁: 42
結束頁: 49
Appears in Collections:Articles